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Ch. 8 - Molecular Biology of Transcription and RNA Processing
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
8장, 문제 5b

The following is a portion of an mRNA sequence:
3'-AUCGUCAUGCAGA-5'
Write out the sequence and polarity of the DNA duplex that encodes this mRNA segment. Label the template and coding DNA strands.

검증된 단계별 안내
1
Identify the polarity of the given mRNA sequence. The sequence provided is 3'-AUCGUCAUGCAGA-5', which means it is written in the 3' to 5' direction. However, mRNA is conventionally written in the 5' to 3' direction, so reverse the sequence to 5'-AGACGUTGACGUA-3'.
Determine the complementary DNA strand (template strand) that would have been used to transcribe this mRNA. Remember that RNA pairs adenine (A) with uracil (U) and cytosine (C) with guanine (G). Replace U with T to reflect DNA pairing. The template strand will be complementary to the mRNA sequence.
Write the template DNA strand in the 3' to 5' direction, as DNA is antiparallel to the mRNA. For example, if the mRNA sequence is 5'-AGACGUTGACGUA-3', the template strand will be 3'-TCTGCACTGCAT-5'.
Determine the coding DNA strand, which is the strand complementary to the template strand. The coding strand will have the same sequence as the mRNA (except T replaces U) and will be written in the 5' to 3' direction.
Label the strands clearly: the template strand is the one used to transcribe the mRNA, and the coding strand is the one that matches the mRNA sequence (except for T replacing U).

비슷한 문제에 대한 검증된 영상 답변:

이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.
영상 길이:
3m

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Transcription

Transcription is the process by which the genetic information in DNA is copied into messenger RNA (mRNA). During this process, RNA polymerase synthesizes mRNA from a DNA template strand, following base-pairing rules where adenine (A) pairs with uracil (U) in RNA, and cytosine (C) pairs with guanine (G). Understanding transcription is essential for determining how mRNA sequences are derived from DNA.
추천 영상:
가이드 코스
09:16
Eukaryotic Transcription

DNA Strands and Polarity

DNA consists of two strands that run in opposite directions, known as antiparallel strands. Each strand has a polarity, with one end designated as the 5' end and the other as the 3' end. The template strand is read in the 3' to 5' direction during transcription, while the coding strand, which has the same sequence as the mRNA (except for T instead of U), runs in the 5' to 3' direction. Recognizing the polarity is crucial for accurately writing the corresponding DNA sequence.
추천 영상:
가이드 코스
03:03
Double Strand Breaks

Base Pairing Rules

Base pairing rules dictate how nucleotides pair in DNA and RNA. In DNA, adenine pairs with thymine (A-T) and cytosine pairs with guanine (C-G). In RNA, adenine pairs with uracil (A-U) instead of thymine. These rules are fundamental for determining the complementary DNA sequence that encodes a given mRNA sequence, ensuring accurate transcription and genetic fidelity.
추천 영상:
가이드 코스
03:49
Base Distortions
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