What are the conditions that guide lactate dehydrogenase to convert pyruvate to lactate? In which tissues or organisms does this process occur?

Anaerobic conditions, high NADH/NAD⁺ ratio, and high glycolytic activity. It occurs in muscle cells.

Aerobic conditions and low glycolytic activity. It occurs in liver cells.

Anaerobic conditions and low NADH/NAD⁺ ratio. It occurs in yeast cells.

Aerobic conditions, low NADH/NAD⁺ ratio, and low glycolytic activity. It occurs in plant tissues.