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Ch.10 Proteins Workers of the Cell
Frost - General, Organic and Biological Chemistry 4th Edition
Frost4th EditionGeneral, Organic and Biological ChemistryISBN: 9780134988696당신이 사용하는 게 아니라요?교과서 변경
6장, 문제 54e

Indicate whether each of the following describes a competitive or a noncompetitive inhibitor.
e. Adding more substrate to the reaction restores the enzyme activity.

검증된 단계별 안내
1
Understand the two types of enzyme inhibitors: Competitive inhibitors bind to the active site of the enzyme, competing with the substrate, while noncompetitive inhibitors bind to a different site on the enzyme, altering its function without directly competing with the substrate.
Recognize that in the case of competitive inhibition, increasing the concentration of the substrate can outcompete the inhibitor for the active site, restoring enzyme activity.
In contrast, for noncompetitive inhibition, increasing the substrate concentration does not restore enzyme activity because the inhibitor affects the enzyme's function regardless of substrate presence.
Analyze the statement: 'Adding more substrate to the reaction restores the enzyme activity.' This suggests that the inhibitor's effect can be overcome by increasing substrate concentration, which is characteristic of competitive inhibition.
Conclude that the described scenario corresponds to a competitive inhibitor, as the enzyme activity is restored by adding more substrate.

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이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.
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주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Competitive Inhibition

Competitive inhibition occurs when an inhibitor competes with the substrate for binding to the active site of an enzyme. This type of inhibition can be overcome by increasing the concentration of the substrate, as more substrate molecules can outcompete the inhibitor for the active site, thereby restoring enzyme activity.
추천 영상:
가이드 코스
1:19
Enzyme Inhibition Concept 1

Noncompetitive Inhibition

Noncompetitive inhibition happens when an inhibitor binds to an enzyme at a site other than the active site, altering the enzyme's function regardless of substrate concentration. In this case, adding more substrate does not restore enzyme activity, as the inhibitor's presence affects the enzyme's ability to catalyze the reaction.
추천 영상:
가이드 코스
1:19
Enzyme Inhibition Concept 1

Enzyme Activity

Enzyme activity refers to the rate at which an enzyme catalyzes a reaction. It can be influenced by various factors, including substrate concentration, temperature, pH, and the presence of inhibitors. Understanding how inhibitors affect enzyme activity is crucial for determining the type of inhibition occurring in a biochemical reaction.
추천 영상:
가이드 코스
1:06
Factors Affecting Enzyme Activity Concept 1