Which combination of attributes would most increase your confidence that a nutrition finding is robust and applicable to clinical advice?

• A. Peer-reviewed publication, human randomized trials with adequate sample size, similar participant demographics to the target population, independent replication, and transparent funding disclosures without vested commercial interests.
• B. Single small animal study with dramatic effect size, press release from a commercial sponsor, and no available conflict of interest statement.
• C. Study funded by the manufacturer that shows no conflict of interest because researchers are independent by title only and therefore the funding is irrelevant.
• D. Highly shareable influencer post showing before-and-after pictures, paid ads, and enthusiastic testimonials from product buyers.

Answer: (A)