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Water and Minerals: Essential Nutrients for Human Health

Study Guide - Smart Notes

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Water

Body Water Distribution and Factors Affecting It

Water is a vital component of the human body, comprising 45-75% of an average adult's body weight. The percentage varies based on several factors:

  • Body Composition: Muscle tissue contains about 75% water, while fat tissue contains only 1-20% water.

  • Age: Elderly individuals have less body water due to decreased muscle mass.

  • Gender: Males typically have a higher percentage of body water than females because they have more muscle and less fat.

Functions of Water

  • Universal Solvent: Dissolves and transports nutrients and waste products.

  • Maintains Body Temperature: Regulates heat through sweating and respiration.

  • Lubricant: Cushions joints and tissues.

  • Cushion for Cells: Protects organs and tissues from shock.

Body Water Compartments

  • Extracellular Fluid: Located outside cells, including blood plasma. Regulated mainly by sodium (Na) and chloride (Cl).

  • Intracellular Fluid: Located inside cells. Regulated mainly by potassium (K) and phosphate (P).

  • Most body water is found inside cells (intracellular).

Sources of Water

  • Fluids: Milk, juices, coffee, tea, and other beverages.

  • Foods: Fruits and vegetables are significant sources.

  • Metabolic Water: Produced during cellular respiration (Krebs cycle).

Diuretic Effects and Fluid Regulation

  • ADH (Anti-diuretic Hormone): Promotes water retention in the kidneys.

  • Caffeine: Mild diuretic; does not typically cause dehydration.

  • Alcohol: Strong diuretic; increases urine output and risk of dehydration.

Recommended Fluid Intake

  • Males: 13 cups (about 3 liters) per day.

  • Females: 9 cups (about 2.2 liters) per day.

Major Minerals

General Characteristics

  • Inorganic: Do not contain carbon; not destroyed by heat or light.

  • Food Content: Amount in food depends on soil composition.

  • Functions: Essential for bone and teeth structure, fluid balance, and as cofactors for enzyme activity.

  • Absorption: Minerals can compete with each other for absorption in the digestive tract.

Calcium

  • Distribution: 99% in bones and teeth; 1% in blood and soft tissues.

  • Association: Phosphorus is commonly found with calcium in bones and teeth.

  • Most Abundant Mineral: Calcium is the most abundant mineral in the body.

  • Absorption: Enhanced by vitamin D, lactose, and phosphorus.

  • Functions:

    • Provides skeletal strength

    • Maintains fluid and electrolyte balance for nerve transmission

    • Muscle contraction and prevention of spasms

    • Acts as a cofactor in enzyme systems

  • Bone Mass Density: Peaks at ages 20-30; bone loss accelerates in women after menopause.

Calcium Deficiency: Osteoporosis

  • Diagnosis: DXA (dual-energy x-ray absorptiometry) scan.

  • Risk Factors: Inadequate calcium and vitamin D intake, genetics, lack of weight-bearing exercise, smoking, excessive alcohol use, eating disorders.

Calcium Supplements

  • Calcium Carbonate: Most common supplement form; maximum absorption per dose is 500 mg.

  • Calcium-Fortified Orange Juice: Must be shaken well before pouring to ensure even distribution.

Food Sources and Bioavailability

  • Dairy: 1 cup of milk or yogurt provides about 300 mg of calcium; bioavailability is 20-30%.

  • Vegetables: Kale has higher bioavailability (40%) than spinach, which is low due to oxalates and phytates that bind calcium.

Magnesium

  • Location: Most magnesium is stored in bones and teeth.

  • Function: Essential for healthy bone metabolism.

  • Food Sources: Dark green, leafy vegetables.

  • Supplements: Many adults do not meet recommended intake; doses over 350 mg/day may cause diarrhea.

Sodium

  • Location: Primarily found outside cells (extracellular fluid).

  • Function: Maintains water balance in the body.

  • Chloride: Usually found with sodium as sodium chloride (NaCl, table salt).

  • Toxicity: Excess sodium can cause hypertension (high blood pressure) in some individuals.

  • DASH Diet: Dietary Approach to Stop Hypertension; emphasizes low sodium, high potassium, reduced processed foods, and increased fruit intake.

  • Other Factors: Weight loss and genetics can influence blood pressure.

  • Deficiency: Can cause muscle cramps.

Microminerals (Trace Minerals)

General Characteristics

  • Needed in small amounts but essential for health.

  • Can be toxic if consumed in excess.

Iron

  • Most Abundant Trace Mineral: Most iron is found in hemoglobin of red blood cells.

  • Function: Transports oxygen to all cells.

  • Absorption:

    • Heme iron (from red meat) is better absorbed than non-heme iron (from plants).

    • Absorption increases with greater need for iron and adequate stomach acid (HCl).

Iron Deficiency

  • Most Common Deficiency Worldwide

  • Symptoms: Fatigue, increased infections, headaches, pale skin, intolerance to cold.

  • High-Risk Groups: Pregnant women, women of child-bearing age, vegans, children, individuals with blood loss.

  • RDA: Women: 18 mg/day; Men: 8 mg/day.

Iron Toxicity

  • Hemochromatosis: Genetic disorder causing excessive iron absorption.

Food Sources of Iron

  • Best Bioavailability: Red meat (heme iron), e.g., hamburger.

  • Other Sources: Egg yolk, dark green vegetables, peas, legumes, molasses, dark chicken meat.

  • Cooking Tip: Simmering tomato sauces in an iron skillet increases iron content.

Other Trace Minerals

Mineral

Functions

Sources

Deficiency

Toxicity

Zinc

DNA & RNA synthesis, immune system function

Oysters, red meat, whole grains (less in fruits & vegetables)

Impaired immunity, delayed wound healing (Additional info: not specified in original notes)

Can cause nausea, vomiting, immune suppression (Additional info: not specified in original notes)

Selenium

Antioxidant

Brazil nuts, seafood, grains (depends on soil concentration)

Possible heart damage

Brittle nails & hair

Fluoride

Prevents tooth decay, strengthens bones

Fluoridated water

Tooth cavities

Joint stiffness, osteoporosis

Additional info:

  • Some deficiency and toxicity symptoms for zinc were inferred based on standard nutrition knowledge.

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