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Eicosanoids definitions

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  • Eicosanoids
    Fatty acid-based lipids derived from C20 polyunsaturated fatty acids, acting as paracrine hormones with diverse biological effects.
  • Arachidonic Acid
    C20 polyunsaturated fatty acid serving as the precursor for all major eicosanoid classes, featuring multiple double bonds.
  • Prostaglandins
    Eicosanoids containing a 5-carbon cyclopentane ring, involved in pain, fever, inflammation, blood flow, and smooth muscle regulation.
  • Thromboxanes
    Eicosanoids with a 6-membered ring and ether group, produced by platelets and crucial for blood clot formation and flow reduction.
  • Leukotrienes
    Eicosanoids with three conjugated double bonds, mainly produced by leukocytes, acting as potent biosignals in allergic reactions and asthma.
  • Cyclopentane Ring
    Five-carbon ring structure found in prostaglandins, distinguishing them from other eicosanoid classes.
  • Ether Group
    Functional group present in thromboxanes' 6-membered ring, contributing to their unique chemical properties.
  • Conjugated Double Bonds
    Adjacent double bonds in leukotrienes, enabling strong biosignaling and smooth muscle contraction effects.
  • Paracrine Hormones
    Signaling molecules acting locally on nearby cells, requiring only low concentrations for biological activity.
  • Platelets
    Cell fragments responsible for producing thromboxanes, playing a key role in blood clotting processes.
  • Leukocytes
    White blood cells that synthesize leukotrienes, mediating immune responses and allergic reactions.
  • Blood Clot
    Aggregated mass formed by platelets and thromboxanes to prevent excessive blood loss after injury.
  • Smooth Muscle Contraction
    Physiological response regulated by prostaglandins and leukotrienes, affecting organs like blood vessels and lungs.
  • Inflammation
    Biological process modulated by prostaglandins, characterized by redness, swelling, and pain.
  • Asthma
    Condition marked by excessive leukotriene production, leading to strong lung smooth muscle contractions and breathing difficulty.