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Negative Feedback definitions

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  • Negative Feedback
    Cellular mechanism where a product reduces its own synthesis by inhibiting an earlier step in its pathway, preventing excess accumulation.
  • Feedback Inhibition
    Regulatory process in which a pathway's end product suppresses activity of an enzyme involved in its formation.
  • Biochemical Regulation
    Control of cellular reactions to maintain balance and efficiency, often achieved through inhibitory mechanisms.
  • Metabolic Pathway
    Series of enzyme-catalyzed reactions converting substrates to products, often regulated to avoid waste.
  • Allosteric Enzyme
    Protein whose activity is modulated by molecules binding at sites other than the active site, affecting pathway flow.
  • Allosteric Site
    Region on an enzyme distinct from the active site where regulatory molecules attach, altering enzyme function.
  • Active Site
    Location on an enzyme where substrate molecules bind and undergo chemical transformation.
  • Inhibitor
    Molecule that decreases enzyme activity, often by binding to a regulatory site and slowing reaction rates.
  • Michaelis Menten Enzyme
    Enzyme following classic kinetics, typically not regulated by allosteric mechanisms in metabolic pathways.
  • Product Concentration
    Amount of a final molecule present in a pathway, which can trigger regulatory responses if levels become excessive.
  • Red Light
    Metaphor for a regulatory signal that slows or halts a metabolic pathway, preventing overproduction.
  • Enzyme Kinetics
    Study of reaction rates and regulatory influences on enzymes within metabolic pathways.
  • Pathway Inhibition
    Suppression of a sequence of biochemical reactions, often initiated by accumulation of a pathway's product.