Question 1

Which of the following best describes pleiotropy, as illustrated in the provided materials?

Accepted Answer

A single gene affects multiple, seemingly unrelated phenotypic traits.

Question 2

In the context of the ABO blood group system, which genotype will result in the AB blood type phenotype?

Accepted Answer

$$I^A I^B$$

Question 3

A cross between two dihybrid Labrador retrievers ($$BbEe 	imes BbEe) $$produces offspring with a phenotypic ratio of 9:3:4. What genetic phenomenon explains the 4 in this ratio?

Accepted Answer

Recessive epistasis

Question 4

Which of the following best explains why the distribution of skin color in humans forms a bell-shaped curve, as shown in the materials?

Accepted Answer

Skin color is determined by polygenic inheritance, where multiple genes contribute additively to the phenotype.

Question 5

A man with blood type A ($$I^A i) $$and a woman with blood type B ($$I^B i) $$have a child. What is the probability that their child will have blood type O?

Accepted Answer

$$\frac{1}{4}$$

Question 6

In a cross between a full-colored rabbit ($$C c$$^{ch}$$) and a light gray rabbit (c$$^{ch}$$ c$$), what is the expected phenotypic ratio among the offspring?

Accepted Answer

1 full color : 1 light gray

Question 7

Which of the following is an example of genomic imprinting?

Accepted Answer

The phenotype of a trait depends on whether the allele is inherited from the mother or the father.

Question 8

Which syndrome is associated with mental retardation, hypotonia, obesity, and male hypogenitalism due to genomic imprinting?

Accepted Answer

Prader-Willi syndrome

Question 9

If two heterozygous dihybrid white dogs ($$IiBb 	imes IiBb) $$are crossed, what is the probability of obtaining a white puppy that is homozygous at both loci ($$IIBB$$)?

Accepted Answer

$$\frac{1}{16}$$

Question 10

Which of the following best describes the relationship between the $$b$$, $$cn$$, and $$vg$$ genes shown on the chromosome in the first image?

Accepted Answer

They are linked genes located on the same chromosome.

Question 11

A child is born with Angelman syndrome. Which of the following is the most likely genetic explanation?

Accepted Answer

A deletion or mutation in the maternal chromosome 15 region that is imprinted.

Question 12

Which of the following is NOT a possible genotype for a person with blood type B?

Accepted Answer

$$I^A I^B$$

Question 13

Which of the following best explains why the phenotypic ratio for a dihybrid cross involving recessive epistasis is 9:3:4 instead of the classic 9:3:3:1?

Accepted Answer

The presence of a homozygous recessive genotype at one locus masks the expression of alleles at the second locus.

Question 14

Which of the following is an example of a quantitative character in humans?

Accepted Answer

Height

Question 15

If a gene has multiple alleles in a population, which of the following is true?

Accepted Answer

There are more than two possible alleles for the gene, but each individual can only have two alleles.

Question 16

Which of the following best describes the dominance hierarchy in rabbit coat color genetics?

Accepted Answer

$$C \u003e c$$^{ch}$$ \u003e ch \u003e c$$

Question 17

Which of the following is a correct statement about linkage?

Accepted Answer

Linked genes tend to be inherited together because they are located close to each other on the same chromosome.

Question 18

Which of the following is a real-life example of pleiotropy?

Accepted Answer

A single gene mutation causing both sickle-shaped red blood cells and resistance to malaria.

Question 19

Which of the following best explains why the offspring of two $$AaBbCc$$ individuals for skin color show a wide range of phenotypes?

Accepted Answer

Each gene pair contributes additively to the phenotype, resulting in many possible combinations.

Question 20

Which of the following is NOT a feature of polygenic inheritance?

Accepted Answer

Each gene has a large, discrete effect on the phenotype.

Advanced Patterns of Inheritance: Pleiotropy, Epistasis, Multiple Alleles, Polygenic Inheritance, and Genomic Imprinting

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