Problem 1
Which of the following is not a property of DNA polymerase?
a. It adds dNTPs only in the 5'→3' direction.
b. It requires a primer to begin synthesis.
c. It opens the two strands of DNA at the replication fork.
d. Its exonuclease activity is involved in proofreading.
Problem 2
What is the function of primase?
a. Synthesis of the repetitive, short double-stranded DNA sequences required by DNA polymerase.
b. Synthesis of a short RNA strand that is complementary to single-stranded DNA.
c. Closing the gap at the 3′ end of DNA after excision repair.
d. Removing primers and synthesizing a short section of DNA to replace them.
Problem 3
How are Okazaki fragments synthesized?
a. By using the leading-strand template, and synthesizing 5'→3'
b. By using the leading-strand template, and synthesizing 3'→5'
c. By using the lagging-strand template, and synthesizing 5'→3'
d. By using the lagging-strand template, and synthesizing 3'→5'.
Problem 4
Telomerase synthesizes DNA in the _____ direction.
Problem 5
Researchers design experiments so that only one thing is different between the treatments that are being compared. In the Hershey–Chase experiment, what was this single difference?
Problem 6
Analyze the following statements about DNA synthesis. Select True or False for each statement.
T/F An RNA polymerase is essential for DNA synthesis.
T/F Okazaki fragments would be unnecessary if DNA polymerase could synthesize DNA in both the 3'→5' and 5'→3' directions.
T/F DNA ligase is used more frequently on the lagging strand than on the leading strand.
T/F Toposiomerase is required to separate the two strands of DNA at the replication fork.
Problem 7
How does telomerase prevent linear chromosomes from shortening during replication?
- How does telomerase prevent linear chromosomes from shortening during replication?
Problem 7
Ch. 15 - DNA and the Gene: Synthesis and Repair
