Domanda del libro di testo
What is the sequence of atoms along the "backbone" of a protein?
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Ch.18 Amino Acids and Proteins
McMurry8th EditionFundamentals of General, Organic, and Biological ChemistryISBN: 9780134015187
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TOC.tableOfContents
- Ch.1 Matter and Measurements27
- Ch.2 Atoms and the Periodic Table20
- Ch.3 Ionic Compounds8
- Ch.4 Molecular Compounds23
- Ch.5 Classification & Balancing of Chemical Reactions12
- Ch.6 Chemical Reactions: Mole and Mass Relationships28
- Ch.7 Chemical Reactions: Energy, Rate and Equilibrium64
- Ch.8 Gases, Liquids and Solids24
- Ch.9 Solutions52
- Ch.10 Acids and Bases25
- Ch.11 Nuclear Chemistry22
- Ch.12 Introduction to Organic Chemistry: Alkanes57
- Ch.13 Alkenes, Alkynes, and Aromatic Compounds47
- Ch.14 Some Compounds with Oxygen, Sulfur, or a Halogen50
- Ch.15 Aldehydes and Ketones45
- Ch.16 Amines42
- Ch.17 Carboxylic Acids and Their Derivatives57
- Ch.18 Amino Acids and Proteins82
- Ch.19 Enzymes and Vitamins63
- Ch.20 Carbohydrates44
- Ch.21 The Generation of Biochemical Energy65
- Ch.22 Carbohydrate Metabolism45
- Ch.23 Lipids42
- Ch.24 Lipid Metabolism33
- Ch.25 Protein and Amino Acid Metabolism24
- Ch.26 Nucleic Acids and Protein Synthesis45
McMurry8th EditionFundamentals of General, Organic, and Biological ChemistryISBN: 9780134015187Non è quello che usi tu?Cambia libro di testo
Capitolo 18, Problema 68a
Bradykinin, a peptide that helps to regulate blood pressure, has the primary structure Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg.
a. Draw the complete structural formula of bradykinin.
Guida verificata passo dopo passo1
Understand that bradykinin is a peptide, which is a chain of amino acids linked by peptide bonds. Each amino acid in the sequence is represented by its three-letter abbreviation: Arg (arginine), Pro (proline), Gly (glycine), Phe (phenylalanine), and Ser (serine).
To draw the complete structural formula, start by identifying the general structure of an amino acid: an amino group (-NH₂), a carboxyl group (-COOH), a hydrogen atom, and a unique side chain (R group) attached to a central carbon atom (α-carbon).
Connect the amino acids in the given sequence (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) using peptide bonds. A peptide bond is formed by a condensation reaction between the carboxyl group of one amino acid and the amino group of the next, releasing a molecule of water (H₂O).
For each amino acid, include its specific side chain (R group) in the structure. For example, arginine (Arg) has a guanidino group, proline (Pro) has a cyclic structure, glycine (Gly) has a hydrogen atom as its side chain, phenylalanine (Phe) has a benzyl group, and serine (Ser) has a hydroxymethyl group.
Ensure the structure starts with a free amino group (-NH₂) at the N-terminus (arginine) and ends with a free carboxyl group (-COOH) at the C-terminus (arginine). Verify that all atoms are correctly bonded and that the structure reflects the sequence provided.
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Peptide Structure
Peptides are short chains of amino acids linked by peptide bonds. The primary structure of a peptide, like bradykinin, refers to the specific sequence of amino acids that determines its unique properties and functions. Understanding how to represent this sequence in a structural formula is essential for visualizing the molecule's composition.
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Percorso guidato
3:07
Peptides Concept 1
Amino Acids
Amino acids are the building blocks of peptides and proteins, each characterized by a central carbon atom, an amino group, a carboxyl group, and a unique side chain (R group). The sequence and properties of these amino acids influence the peptide's structure and biological activity. In bradykinin, the specific arrangement of its amino acids is crucial for its role in regulating blood pressure.
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Percorso guidato
3:03Amino Acid Catabolism: Amino Group Example 2
Structural Formula Representation
The structural formula of a molecule provides a visual representation of its atomic arrangement and bonding. For peptides, this includes depicting the backbone of amino acids and the side chains. Accurately drawing the structural formula of bradykinin involves illustrating the peptide bonds between amino acids and the functional groups that contribute to its biological function.
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Percorso guidato
1:01Structural Formula Concept 2
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Identify the amino acids present in the peptide shown and name the peptide using the three-letter abbreviations.
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Domanda del libro di testo
Bradykinin, a peptide that helps to regulate blood pressure, has the primary structure Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg.
b. Bradykinin has a very kinked secondary structure. Why?
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