The route by which substances are reabsorbed by crossing through the cells of the renal tubule and collecting system is known as the:
a. Paracellular route
b. Transcellular route
c. Primary active transport route
d. Facultative route

검증된 단계별 안내

Understand the context: The question is about the reabsorption of substances in the kidneys, specifically in the renal tubule and collecting system. Reabsorption involves moving substances from the filtrate back into the blood.

Review the two main routes of reabsorption: (1) The paracellular route, where substances pass between adjacent cells, and (2) the transcellular route, where substances pass through the cells themselves, crossing both the apical and basolateral membranes.

Clarify the mechanisms: The transcellular route often involves active or passive transport mechanisms, such as primary active transport (e.g., sodium-potassium pumps) or facilitated diffusion, depending on the substance being reabsorbed.

Eliminate incorrect options: (a) The paracellular route involves movement between cells, not through them. (c) Primary active transport is a mechanism, not a route. (d) Facultative reabsorption refers to water reabsorption regulated by hormones like ADH, not a specific route.

Conclude: The correct answer is the transcellular route, as it describes the process of substances crossing through the cells of the renal tubule and collecting system.

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주요 개념

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Renal Tubule Function

The renal tubule is a critical component of the nephron in the kidney, responsible for the reabsorption of water, ions, and nutrients from the filtrate back into the bloodstream. Understanding its structure and function is essential for grasping how substances are processed in the kidney.

Reabsorption Mechanisms

Reabsorption in the renal tubule occurs through two primary mechanisms: paracellular and transcellular routes. The paracellular route involves substances passing between cells, while the transcellular route requires substances to cross the cell membrane, often involving transport proteins and energy.

Active Transport

Active transport is a process that moves substances against their concentration gradient, requiring energy, typically in the form of ATP. This mechanism is crucial for the reabsorption of certain ions and molecules in the renal tubule, distinguishing it from passive transport methods.

The route by which substances are reabsorbed by crossing through the cells of the renal tubule and collecting system is known as the:a. Paracellular routeb. Transcellular routec. Primary active transport routed. Facultative route