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Ch. 25 - Quantitative Genetics and Multifactorial Traits
Klug - Concepts of Genetics 12th Edition
Klug12th EditionConcepts of GeneticsISBN: 9780135564776당신이 사용하는 게 아니라요?교과서 변경
25장, 문제 6e

An inbred strain of plants has a mean height of 24 cm. A second strain of the same species from a different geographic region also has a mean height of 24 cm. When plants from the two strains are crossed together, the F₁ plants are the same height as the parent plants. However, the F₂ generation shows a wide range of heights; the majority are like the P₁ and F₁ plants, but approximately 4 of 1000 are only 12 cm high and about 4 of 1000 are 36 cm high.
Indicate three possible genotypes that could account for F₂ plants that are 18 cm high and three that account for F₂ plants that are 33 cm high.

검증된 단계별 안내
1
Step 1: Understand the genetic context. The problem involves two inbred strains with the same mean height (24 cm), their F₁ offspring also have 24 cm height, and the F₂ generation shows variation including extreme heights (12 cm and 36 cm). This suggests that height is controlled by multiple genes (polygenic inheritance) with additive effects.
Step 2: Define the genetic model. Assume that each gene contributes additively to the height. For example, each gene has two alleles: a 'plus' allele (+) that adds a certain amount to height and a 'minus' allele (-) that adds less or subtracts. The parental strains are homozygous but differ in alleles, so crossing them produces heterozygous F₁ with intermediate height.
Step 3: Determine the genotypes for extreme phenotypes. The shortest plants (12 cm) likely have all 'minus' alleles (e.g., all --), and the tallest plants (36 cm) have all 'plus' alleles (e.g., all ++). The F₁ plants are heterozygous at all loci (e.g., all +-), resulting in the intermediate height (24 cm).
Step 4: Calculate intermediate heights (18 cm and 33 cm). Since height is additive, plants with genotypes having fewer 'plus' alleles than F₁ but more than the shortest will have intermediate heights. For 18 cm, identify genotypes with one fewer 'plus' allele than F₁; for 33 cm, genotypes with one more 'plus' allele than F₁ but fewer than the tallest.
Step 5: List three possible genotypes for each intermediate height. For 18 cm, genotypes could be those with one locus homozygous 'minus' and others heterozygous (e.g., -- + - + -), or heterozygous at all loci except one homozygous 'minus'. For 33 cm, genotypes could be those with one locus homozygous 'plus' and others heterozygous (e.g., ++ + - + -), or heterozygous at all loci except one homozygous 'plus'.

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주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Quantitative Trait Inheritance

Quantitative traits, like plant height, are controlled by multiple genes (polygenes) and show continuous variation. The F₂ generation often displays a range of phenotypes due to the combination of alleles from both parents, resulting in intermediate and extreme trait values.
추천 영상:
가이드 코스
13:40
Traits and Variance

Genotype-Phenotype Relationship in Polygenic Traits

In polygenic inheritance, each gene contributes additively to the phenotype. Different combinations of alleles produce a spectrum of phenotypes, where specific genotypes correspond to particular trait values, such as intermediate or extreme heights in the F₂ plants.
추천 영상:
가이드 코스
13:40
Traits and Variance

Segregation and Recombination in F₂ Generation

During the formation of the F₂ generation, alleles segregate and recombine independently, creating new genotype combinations. This leads to phenotypic variation, including rare extreme phenotypes and intermediate heights, reflecting the underlying genetic diversity.
추천 영상:
가이드 코스
03:51
Recombination after Single Strand Breaks
관련 실천
교과서 질문

In the following table, average differences of height, weight, and fingerprint ridge count between monozygotic twins (reared together and apart), dizygotic twins, and nontwin siblings are compared: 

Based on the data in this table, which of these quantitative traits has the highest heritability values?

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교과서 질문

An inbred strain of plants has a mean height of 24 cm. A second strain of the same species from a different geographic region also has a mean height of 24 cm. When plants from the two strains are crossed together, the F₁ plants are the same height as the parent plants. However, the F₂ generation shows a wide range of heights; the majority are like the P₁ and F₁ plants, but approximately 4 of 1000 are only 12 cm high and about 4 of 1000 are 36 cm high.

How many gene pairs are involved?

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views
교과서 질문

An inbred strain of plants has a mean height of 24 cm. A second strain of the same species from a different geographic region also has a mean height of 24 cm. When plants from the two strains are crossed together, the F₁ plants are the same height as the parent plants. However, the F₂ generation shows a wide range of heights; the majority are like the P₁ and F₁ plants, but approximately 4 of 1000 are only 12 cm high and about 4 of 1000 are 36 cm high.

How much does each gene contribute to plant height?

620
views
교과서 질문

Erma and Harvey were a compatible barnyard pair, but a curious sight. Harvey's tail was only 6 cm long, while Erma's was 30 cm. Their F₁ piglet offspring all grew tails that were 18 cm. When inbred, an F₂ generation resulted in many piglets (Erma and Harvey's grandpigs), whose tails ranged in 4-cm intervals from 6 to 30 cm (6, 10, 14, 18, 22, 26, and 30). Most had 18-cm tails, while 1/64 had 6-cm tails and 1/64 had 30-cm tails.

If one of the 18-cm-tail F₁ pigs is mated with one of the 6-cm-tail F₂ pigs, what phenotypic ratio will be predicted if many offspring resulted? Diagram the cross.

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교과서 질문

An inbred strain of plants has a mean height of 24 cm. A second strain of the same species from a different geographic region also has a mean height of 24 cm. When plants from the two strains are crossed together, the F₁ plants are the same height as the parent plants. However, the F₂ generation shows a wide range of heights; the majority are like the P₁ and F₁ plants, but approximately 4 of 1000 are only 12 cm high and about 4 of 1000 are 36 cm high.

Indicate one possible set of genotypes for the original P₁ parents and the F₁ plants that could account for these results.

623
views
교과서 질문

Erma and Harvey were a compatible barnyard pair, but a curious sight. Harvey's tail was only 6 cm long, while Erma's was 30 cm. Their F₁ piglet offspring all grew tails that were 18 cm. When inbred, an F₂ generation resulted in many piglets (Erma and Harvey's grandpigs), whose tails ranged in 4-cm intervals from 6 to 30 cm (6, 10, 14, 18, 22, 26, and 30). Most had 18-cm tails, while 1/64 had 6-cm tails and 1/64 had 30-cm tails.

Explain how these tail lengths were inherited by describing the mode of inheritance, indicating how many gene pairs were at work, and designating the genotypes of Harvey, Erma, and their 18-cm-tail offspring.

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