Where are the mechanoreceptors that sense stomach fullness primarily located and what is their primary neural pathway to the brain?

Mechanoreceptors are spread throughout skeletal muscle and signal fullness through somatic reflex arcs that directly modulate satiety center activity.

Mechanoreceptors are exclusively located in the colon and use sympathetic efferents to inform the frontal cortex about satiety.

Mechanoreceptors are located in the stomach and small intestine wall and signal the brain primarily via vagal afferent pathways to hypothalamic centers.

Mechanoreceptors are located in the liver capsule and communicate fullness through hepatic portal hormones rather than neural routes.