Microbiology
All healthy adults over age 25, since live attenuated vaccines invariably revert to a pathogenic form in older individuals.
Only individuals with prior allergic reactions to inactivated vaccines, because allergies are the primary contraindication for all attenuated vaccines.
People who have previously received antibiotics for any infection within the past year, because antibiotics neutralize vaccine efficacy in live attenuated preparations.
Pregnant individuals and people with severe immunocompromise (e.g., high-dose corticosteroids or advanced HIV with low CD4 counts) because of risk to fetus or inability to control replicating vaccine strains.
