What is the difference between upstream and downstream in relation to transcription?

• A. Upstream sequences are located within the gene body, while downstream sequences are outside the gene body.
• B. Downstream sequences are in the direction of transcription, while upstream sequences are in the opposite direction.
• C. Upstream sequences are involved in transcription initiation, while downstream sequences are involved in transcription termination.
• D. Downstream sequences are part of the coding region, while upstream sequences are part of the non-coding region.

Answer: (B)