A child is bitten by a potentially rabid animal. The clinician gives immediate human rabies immunoglobulin and begins a multi-dose rabies vaccine series. According to decision rules, what types of acquired immunity are provided by the immunoglobulin and the vaccine respectively?

• A. Immunoglobulin—naturally acquired passive immunity; Vaccine—naturally acquired active immunity because both occur in response to contact with an infectious animal.
• B. Immunoglobulin—artificially acquired passive immunity; Vaccine—artificially acquired active immunity.
• C. Immunoglobulin—artificially acquired active immunity due to immune stimulation by donor antibodies; Vaccine—artificially acquired passive immunity because vaccines sometimes contain adjuvants that mimic passive transfer.
• D. Immunoglobulin—artificially acquired passive immunity; Vaccine—naturally acquired active immunity because immunization is considered a natural process of antigen exposure when administered shortly after exposure.

Answer: (B)