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Introduction to Transcription definitions

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  • Transcription

    Synthesis of RNA using a DNA template, starting at a promoter and ending at a terminator, producing an RNA molecule complementary to the template strand.
  • Promoter

    DNA sequence where RNA polymerase binds to initiate RNA synthesis, marking the start site for transcription.
  • Terminator

    DNA sequence signaling the end of transcription, causing RNA polymerase to release the newly made RNA.
  • RNA Polymerase

    Enzyme responsible for building RNA from DNA, attaching at the promoter and synthesizing RNA without a primer.
  • Gene

    Segment of DNA containing coding, promoter, and terminator regions, encoding a functional product such as a protein.
  • Coding Strand

    DNA strand with the same sequence as the RNA transcript, except thymine is replaced by uracil in RNA.
  • Template Strand

    DNA strand used as a guide for RNA synthesis, ensuring the RNA sequence is complementary to it.
  • Pre-mRNA

    Initial RNA product in eukaryotes, requiring further processing before becoming a mature messenger RNA.
  • Directionality

    Orientation of DNA or RNA, described as 5' to 3', determining the direction of synthesis and transcription.
  • Upstream

    DNA region located opposite to the direction of transcription, relative to a gene's promoter.
  • Downstream

    DNA region located in the same direction as transcription, following the gene's terminator.
  • Watson and Crick Base Pairing

    Rule dictating how nucleotides pair: adenine with uracil (in RNA) or thymine (in DNA), and guanine with cytosine.
  • RNA Nucleotide

    Building block of RNA, consisting of a ribose sugar, phosphate group, and a nitrogenous base (A, U, G, or C).
  • RNA-DNA Hybrid Region

    Temporary area during transcription where newly synthesized RNA is base-paired with the DNA template strand.
  • Messenger RNA

    RNA molecule carrying genetic information from DNA to the ribosome, guiding protein synthesis.