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Smallpox quiz
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Define:
What virus causes smallpox?
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What virus causes smallpox?
Smallpox is caused by the variola virus, a double-stranded DNA virus in the genus Orthopoxvirus.
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What virus causes smallpox?
Smallpox is caused by the variola virus, a double-stranded DNA virus in the genus Orthopoxvirus.
How does smallpox initially enter the human body?
Smallpox initially enters the body through the upper respiratory tract.
How does the variola virus spread throughout the body after initial infection?
The virus spreads systemically via the blood and lymphatic system, infecting organs and the skin.
What are the characteristic skin symptoms of smallpox?
Smallpox causes a severe skin rash with lesions that progress from vesicles to pustules, often resulting in severe scarring.
How is smallpox transmitted from person to person?
Smallpox spreads mainly through inhalation of respiratory droplets and direct contact with lesions or contaminated materials.
How does the contagiousness of smallpox compare to measles?
Smallpox is less contagious than measles but much more deadly.
What was the estimated global death toll from smallpox in the twentieth century?
Smallpox caused an estimated 300 to 500 million deaths worldwide in the twentieth century.
What is the fatality rate of smallpox in unvaccinated individuals?
The fatality rate is about 30% in unvaccinated individuals.
What are the initial symptoms of smallpox before the rash appears?
Initial symptoms include high fever, fatigue, and malaise.
How was smallpox primarily diagnosed before its eradication?
Diagnosis was mainly based on the visual appearance and distribution of skin lesions.
What type of treatment was available for smallpox before eradication?
Treatment was supportive, focusing on symptom management and patient isolation; there was no specific antiviral therapy.
How can immunity to smallpox be achieved?
Immunity can be achieved through vaccination with the smallpox vaccine.
What year was smallpox declared eradicated worldwide?
Smallpox was declared eradicated in 1980.
Why is smallpox eradication considered a major milestone in public health?
It was the first and only human disease to be fully eradicated, demonstrating the effectiveness of vaccination.
What organs and tissues can smallpox damage besides the skin?
Smallpox can damage blood vessels, immune tissues, the liver, and the lungs.