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Comprehensive Study Notes: Principles of Disease, Pathogenicity, Immunity, Vaccines, and Antimicrobial Drugs

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Characteristics of Infectious Disease

  • Primary vs. Secondary Infections
    04:16
  • Communicable vs. Noncommunicable Diseases
    04:57
  • Intro to Characteristics of Infectious Disease
    05:09

Disease Transmission

  • Disease Transmission
    01:24
  • Vertical vs. Horizontal Disease Transmission
    02:32

Horizontal Disease Transmission

  • Horizontal Disease Transmission Example 1
    01:53
  • Zoonoses vs. Vector-Borne Transmission
    03:52
  • Indirect Transmission
    04:42

Healthcare-Associated Infections

  • Risk Factors Contributing to HAIs
    02:45
  • Healthcare-Associated Infections
    01:33
  • Preventing HAIs
    01:59

Introduction to Epidemiology

  • Introduction to Epidemiology Example 1
    01:48
  • Introduction to Epidemiology Example 2
    05:15
  • Mortality & Case-Fatality Rates
    02:28

Bacterial Pathogenesis

  • Intro to Bacterial Pathogenesis
    02:35
  • 1) Exposure to Pathogen
    03:27
  • 3) Invasion into Host Tissues
    05:38

Introduction to Pathogenic Toxins

  • Introduction to Pathogenic Toxins
    03:40

Exotoxins Cause Damage to the Host

  • 1) A-B Toxins
    04:44
  • Types of Exotoxins
    03:30
  • 3) Superantigens
    03:59

Endotoxin Causes Damage to the Host

  • Endotoxin
    02:46
  • Lipid A Causes Septic Shock
    03:24

Exotoxins vs. Endotoxin Review

  • Exotoxins vs. Endotoxin Review
    07:22

Introduction to Immunity

  • Innate vs. Adaptive Immunity
    05:52
  • Antigens & Antibodies
    02:58

Introduction to Innate Immunity

  • Introduction to Innate Immunity
    02:30
  • Map of Lesson on Innate Immunity
    06:42

Introduction to First-Line Defenses

  • Introduction to First-Line Defenses
    01:56
  • Map of the Lesson on First-Line Defenses
    01:37

Phagoctytosis

  • Steps of Phagocytosis
    08:57
  • Phagoctytosis
    02:19

Introduction to Inflammation

  • Types of Inflammatory Responses
    02:52
  • Introduction to Inflammation
    01:38
  • Chronic Inflammation
    03:09

Fever

  • Fever
    03:57

Interferon Response

  • Interferon Response
    01:32
  • Steps of the Interferon Response
    09:59

Introduction to Adaptive Immunity

  • Overview of Adaptive Immunity
    04:57
  • Primary vs. Secondary Lymphoid Organs
    04:58
  • Introduction to Adaptive Immunity
    05:47

Antigens

  • Free Antigens vs. Presented Antigens on APCs
    04:11
  • Antigens
    03:59

Introduction to B Lymphocytes

  • B cell Receptors
    04:37
  • Naive B cells Become Effector (Plasma) Cells & Memory Cells
    04:23
  • Introduction to B Lymphocytes
    03:55

Antibodies

  • Antibody Structure
    05:40
  • Antibody Diversity
    02:34
  • Antibodies
    00:48

Introduction to T Lymphocytes

  • Cytotoxic T Cells vs. Helper T Cells
    05:58
  • T-Cell Receptors
    05:18
  • Naive T Cells Become Effector & Memory T Cells
    07:56

Review of Cytotoxic vs Helper T Cells

  • Review of Cytotoxic vs Helper T Cells
    04:27
  • Comic Strip for T Cell Functions
    02:58

Primary and Secondary Response of Adaptive Immunity

  • Primary and Secondary Response of Adaptive Immunity
    06:59

Introduction to Vaccines

  • History of Vaccines
    04:19
  • 2 Types of Vaccines
    02:03

Immunotherapy: Monoclonal Antibodies

  • Large-Scale Production on Monoclonal Antibodies
    03:04
  • Immunotherapy: Monoclonal Antibodies Example 1
    02:23
  • Immunotherapy: Monoclonal Antibodies
    02:28

Immunoassay: ELISA

  • Indirect ELISA
    02:50
  • Immunoassay: ELISA
    04:29
  • Direct ELISA (via "Sandwich" Method)
    03:56

Introduction to Antimicrobial Drugs

  • Guided course
    History of Antimicrobial Drugs
    05:33

How Antimicrobial Drugs Work

  • Guided course
    Selective Toxicity
    05:27
  • Guided course
    How Antimicrobial Drugs Work Example 1
    03:28

Inhibitors of Cell Wall Synthesis: Beta-lactam & Penicillin

  • Guided course
    Inhibitors of Cell Wall Synthesis: Beta-lactam & Penicillin Example 3
    04:02
  • Guided course
    Other Beta-lactam Antibiotics
    04:51
  • Inhibitors of Cell Wall Synthesis: Beta-lactam & Penicillin Example 2
    02:21

Inhibitors of Protein Synthesis

  • Guided course
    Inhibitors of Protein Synthesis
    05:25
  • Guided course
    Inhibitors of Protein Synthesis Example 1
    03:04

Disruptors of Cell Membranes

  • Guided course
    Disruptors of Cell Membranes
    04:03

Inhibitors of Nucleic Acid Synthesis

  • Guided course
    Inhibitors of Nucleic Acid Synthesis Example 1
    02:21
  • Guided course
    Inhibitors of Nucleic Acid Synthesis
    05:01

Competitive Inhibitors of Metabolic Pathways

  • Guided course
    Competitive Inhibitors of Metabolic Pathways Example 1
    02:36
  • Guided course
    Sulfa Drugs & Folic Acid Synthesis
    05:22

Antifungal Drugs

  • Guided course
    Antifungal Drugs
    06:43
  • Guided course
    Antifungal Drugs Example 1
    02:06

Antiviral Drugs

  • Guided course
    Antiviral Drugs
    07:25

Antimicrobial Resistance

  • Guided course
    Types of Resistance Mechanisms
    05:04
  • Guided course
    Spread of Antibiotic Resistance
    04:45
  • Guided course
    Antibiotic Resistance
    03:45