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Comprehensive Study Notes: Principles of Disease, Pathogenicity, Immunity, Vaccines, and Antimicrobial Drugs

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Characteristics of Infectious Disease

Disease Transmission

Horizontal Disease Transmission

Healthcare-Associated Infections

Introduction to Epidemiology

Bacterial Pathogenesis

Introduction to Pathogenic Toxins

Exotoxins Cause Damage to the Host

Endotoxin Causes Damage to the Host

Exotoxins vs. Endotoxin Review

Introduction to Immunity

Introduction to Innate Immunity

Introduction to First-Line Defenses

Phagoctytosis

Introduction to Inflammation

Fever

Interferon Response

Introduction to Adaptive Immunity

Antigens

Introduction to B Lymphocytes

Antibodies

Introduction to T Lymphocytes

Review of Cytotoxic vs Helper T Cells

Primary and Secondary Response of Adaptive Immunity

Introduction to Vaccines

Immunotherapy: Monoclonal Antibodies

Immunoassay: ELISA

Introduction to Antimicrobial Drugs

How Antimicrobial Drugs Work

Inhibitors of Cell Wall Synthesis: Beta-lactam & Penicillin

Inhibitors of Protein Synthesis

Disruptors of Cell Membranes

Inhibitors of Nucleic Acid Synthesis

Competitive Inhibitors of Metabolic Pathways

Antifungal Drugs

Antiviral Drugs

Antimicrobial Resistance