Question 1

A patient is undergoing desensitization immunotherapy for a severe pollen allergy. Which of the following statements about this therapy is INCORRECT?

Accepted Answer

It increases the number of IgE molecules in the patient.

Question 2

A patient presents to the ER with tachycardia and a sudden drop in blood pressure after eating shellfish. These are signs of __________ affecting the __________.

Accepted Answer

systemic anaphylaxis; cardiovascular system

Question 3

Most food allergies are only weakly responsive to traditional desensitization therapies. Which of the following best explains why?

Accepted Answer

The immune response to food allergens is primarily IgE-mediated but less accessible to desensitization.

Question 4

Hemolytic disease of the newborn is most likely to occur when:

Accepted Answer

the father is Rh+ and the mother is Rh–

Question 5

Which of the following statements about serum sickness is TRUE?

Accepted Answer

It is caused by the patient’s immune system recognizing the administered substance as foreign.

Question 6

Grave’s disease is a type II hypersensitivity caused by:

Accepted Answer

receptor overactivation

Question 7

A patient receives an incompatible blood transfusion and develops symptoms within hours. Which of the following best describes the risk and timing?

Accepted Answer

A hemolytic transfusion reaction, which lyses red blood cells, could kill the patient. Signs and symptoms tend to occur within hours of incompatible transfusion.

Question 8

Lupus is a __________ hypersensitivity characterized by __________.

Accepted Answer

type III; a rash across cheeks and nose, fatigue, and joint pain

Question 9

Which of the following infectious agents would NOT directly affect immune system cells?

Accepted Answer

Rabies virus

Question 10

Which of the following is an INCORRECT statement about administering RhoGAM to an Rh– mother?

Accepted Answer

RhoGAM will be administered to every Rh– mother after birth, even if her child is Rh–.

Question 11

Which of the following is a TRUE statement about the tuberculin skin test?

Accepted Answer

For the test, PPD is injected into the skin of the forearm.

Question 12

Which of the following is NOT one of the hallmark signs of primary immunodeficiencies?

Accepted Answer

Caused by common infectious agents

Question 13

How are autoimmune disorders diagnosed?

Accepted Answer

A collection of tests and careful assessment of signs and symptoms are required.

Question 14

Which of the following hypersensitivities are characterized by the slowest onset?

Accepted Answer

Type IV

Question 15

A person with blood type A+ can safely donate to a person with blood type __________ and receive from a person with blood type __________.

Accepted Answer

AB+; O+

Question 16

Why is celiac disease characterized as a type IV hypersensitivity and not an allergy?

Accepted Answer

T cells, not IgG, attack the lining to the small intestines within 2-3 days of gluten consumption.

Question 17

Which of the following disorders is considered a “Type II” in the Gell and Coombs classification system?

Accepted Answer

Rheumatic heart disease

Question 18

A patient with a newly transplanted organ is likely prescribed __________ in order to limit the risk of transplant rejection.

Accepted Answer

immunosuppressants

Question 19

Secondary immunodeficiencies are commonly caused by:

Accepted Answer

a decline in immune system rigor

Question 20

In type I hypersensitivities, allergen exposure triggers the immune system to produce __________. This is called the __________.

Accepted Answer

IgE; sensitizing exposure

Question 21

Which of the following is NOT an autoimmune disease?

Accepted Answer

Hemolytic disease of the newborn

Question 22

You are working in the ER and have a patient who needs a blood transfusion. Without knowing the patient's blood type, which of the following blood types would you be able to safely provide?

Accepted Answer

O–

Question 23

___________ are transplants from self, like a self-skin graft from one part of the body to another location.

Accepted Answer

Autografts

Immune System Disorders & Hypersensitivity: Step-by-Step Study Guidance

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