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Innate and Adaptive Immunity, Host-Microbe Interactions, and Biomedical Applications

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Introduction to Innate Immunity

Introduction to First-Line Defenses

Physical Barriers in First-Line Defenses: Skin

Physical Barriers in First-Line Defenses: Mucous Membrane

First-Line Defenses: Chemical Barriers

The Human Microbiome

Cells of the Immune System: Granulocytes

Cells of the Immune System: Agranulocytes

Cell Communication: Cytokines

Interferon Response

Introduction to the Complement System

Activation Pathways of the Complement System

Effects of the Complement System

Introduction to Inflammation

Steps of the Inflammatory Response

Fever

Introduction to Adaptive Immunity

Antigens

Introduction to T Lymphocytes

Major Histocompatibility Complex Molecules

Activation of T Lymphocytes

Functions of T Lymphocytes

Review of Cytotoxic vs Helper T Cells

Introduction to B Lymphocytes

Antibodies

Classes of Antibodies

Outcomes of Antibody Binding to Antigen

T Dependent & T Independent Antigens

Clonal Selection

Primary and Secondary Response of Adaptive Immunity

Immune Tolerance

Regulatory T Cells

Introduction to Immunity

Immunodeficiency Disorders

Autoimmune Diseases

Introduction to Vaccines

Attenuated Vaccines

Inactivated Vaccines

Immunoassay: Fluorescent Antibody Tests

Immunoassay: ELISA

Immunoassay: Western Blotting

Bacterial Pathogenesis

Introduction to Avoiding Host Defense Mechanisms

Biofilms

Introduction to Cultivating Microbial Growth

Disease Transmission