Question 1

Which strain of Chlamydia trachomatis is primarily responsible for attacking the mucous membranes of the eyes, genitourinary tract, and lungs?

Accepted Answer

Trachoma strain

Question 2

A newborn develops conjunctivitis after passing through the birth canal. Which prophylactic treatments are recommended to prevent this condition?

Accepted Answer

Erythromycin and doxycycline

Question 3

Which diagnostic method is LEAST recommended for identifying urogenital Chlamydia trachomatis infections due to low sensitivity and high false-negative rates in asymptomatic patients?

Accepted Answer

Giemsa or iodine stains

Question 4

Which of the following is a disfiguring disease of the external genitalia and pelvic lymphatics caused by Chlamydia trachomatis?

Accepted Answer

Lymphogranuloma venereum

Question 5

A 25-year-old woman presents with pelvic pain and a history of asymptomatic sexually transmitted infection. Which complication is most likely associated with Chlamydia trachomatis?

Accepted Answer

Pelvic inflammatory disease (PID)

Question 6

Which of the following statements about Herpes Simplex Virus (HSV) transmission is correct?

Accepted Answer

Genital herpes can be transmitted in the absence of lesions.

Question 7

Which laboratory finding is most typical for diagnosing severe or disseminated HSV infection?

Accepted Answer

Direct fluorescent antibody tests

Question 8

A neonate is at risk for potentially fatal HSV infection. Which preventative measure is recommended if the mother has active genital lesions at the time of birth?

Accepted Answer

Delivery by C-section

Question 9

Which of the following is TRUE regarding Human Papillomavirus (HPV)?

Accepted Answer

HPV is a non-enveloped double-stranded DNA virus.

Question 10

Which vaccine is approved for the prevention of HPV-related cancers?

Accepted Answer

Gardasil 9

Question 11

A Pap smear is used to screen for abnormal cervical cells. Which virus is this test most relevant for?

Accepted Answer

Human Papillomavirus

Question 12

Which of the following treatments is recommended for chlamydiosis?

Accepted Answer

Doxycycline and azithromycin

Question 13

Which of the following is a common misconception about the transmission of HSV?

Accepted Answer

HSV transmission requires visible lesions.

Question 14

Which of the following is a multi-step diagnostic approach for Chlamydia trachomatis infection?

Accepted Answer

Sampling cells from mucosal surface, followed by immunofluorescence or PCR-based tests

Question 15

Which equation best represents the probability $P$ of a false-negative result in a diagnostic test with sensitivity $S$ and prevalence $Pr$ for Chlamydia trachomatis in asymptomatic patients?

Accepted Answer

$P = 1 - S$

Question 16

Which of the following is a real-world consequence of untreated chlamydiosis in women?

Accepted Answer

Long-term reproductive damage

Question 17

Which of the following best describes the incubation period for HPV after exposure?

Accepted Answer

2 weeks to more than a year

Question 18

Which of the following is a plausible reason why Giemsa or iodine stains are not recommended for urogenital specimens in Chlamydia trachomatis diagnosis?

Accepted Answer

They result in low sensitivity and high false-negative rates.

Question 19

Which of the following is a correct application of preventative screening in pregnant women for HSV?

Accepted Answer

Screening allows for C-section delivery if an outbreak is present at birth.

Question 20

Which of the following is a correct statement about the epidemiology of genital herpes?

Accepted Answer

Active lesions are the most significant source, but transmission can occur without visible lesions.

Microbial Pathogens: Chlamydia trachomatis, Herpes Simplex Viruses, and Human Papillomavirus

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