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Microbiology Exam Study Guide: Immunity, Host-Microbe Interactions, and Diagnostic Methods

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Introduction to Immunity

  • Innate vs. Adaptive Immunity
    05:52
  • Antigens & Antibodies
    02:58

Introduction to Innate Immunity

  • Introduction to Innate Immunity
    02:30
  • Map of Lesson on Innate Immunity
    06:42

Introduction to First-Line Defenses

  • Introduction to First-Line Defenses
    01:56
  • Map of the Lesson on First-Line Defenses
    01:37

Physical Barriers in First-Line Defenses: Skin

  • Physical Barriers in First-Line Defenses: Skin
    01:28
  • Physical Barriers in First-Line Defenses: Skin
    04:08

Physical Barriers in First-Line Defenses: Mucous Membrane

  • Peristalsis & Mucociliary Escalator
    04:16
  • Mucous Membranes
    02:34

First-Line Defenses: Chemical Barriers

  • Chemical Defenses: Gastric Juice Prevents Microbial Growth by Lowering pH
    02:07
  • Chemical Defenses: Earwax Prevents Microbial Growth by Controlling pH
    02:18
  • Chemical Defenses: Sweat Glands Prevent Microbial Growth by Perspiration
    02:04

First-Line Defenses: Normal Microbiota

  • Normal Microbiota
    03:43

Phagoctytosis

  • Steps of Phagocytosis
    08:57
  • Phagoctytosis
    02:19

Introduction to Inflammation

  • Types of Inflammatory Responses
    02:52
  • Introduction to Inflammation
    01:38
  • Chronic Inflammation
    03:09

Steps of the Inflammatory Response

  • 2) Release of Inflammatory Mediators & Other Cytokines
    02:15
  • Damaging Effects of the Inflammatory Response
    02:10
  • 3) Vasodilation
    02:39

Interferon Response

  • Interferon Response
    01:32
  • Steps of the Interferon Response
    09:59

Introduction to the Complement System

  • Map of the Lesson on the Complement System
    03:25
  • Introduction to the Complement System
    04:25
  • Proteins of the Complement System
    04:16

Activation Pathways of the Complement System

  • 2) Lectin Pathway
    03:04
  • 1) Alternative Pathway
    04:40
  • 3) Classical Pathway
    03:42

Effects of the Complement System

  • 1) Opsonization
    04:09
  • 2) Cell Lysis of Invading Microbes
    03:18
  • Effects of the Complement System
    01:32

Review of the Complement System

  • Review of the Complement System
    05:15

Introduction to Adaptive Immunity

  • Overview of Adaptive Immunity
    04:57
  • Primary vs. Secondary Lymphoid Organs
    04:58
  • Introduction to Adaptive Immunity
    05:47

Antigens

  • Free Antigens vs. Presented Antigens on APCs
    04:11
  • Antigens
    03:59

Introduction to T Lymphocytes

  • Cytotoxic T Cells vs. Helper T Cells
    05:58
  • T-Cell Receptors
    05:18
  • Naive T Cells Become Effector & Memory T Cells
    07:56

Major Histocompatibility Complex Molecules

  • Classes of MHC Molecules
    07:17
  • Major Histocompatibility Complex Molecules
    02:31

Activation of T Lymphocytes

  • Activation of T Lymphocytes
    07:33
  • Comic Strip for T Cell Activation
    03:29

Functions of T Lymphocytes

  • Functions of Helper T Cells (TH):Activation of Macrophages
    05:18
  • Types of Helper T Cells (TH)
    03:19
  • Functions of Cytotoxic T Cells (Tc)
    06:21

Review of Cytotoxic vs Helper T Cells

  • Review of Cytotoxic vs Helper T Cells
    04:27
  • Comic Strip for T Cell Functions
    02:58

Introduction to B Lymphocytes

  • B cell Receptors
    04:37
  • Naive B cells Become Effector (Plasma) Cells & Memory Cells
    04:23
  • Introduction to B Lymphocytes
    03:55

Antibodies

  • Antibody Structure
    05:40
  • Antibody Diversity
    02:34
  • Antibodies
    00:48

Classes of Antibodies

  • IgE
    02:45
  • IgA
    02:44
  • Classes of Antibodies
    04:43

Outcomes of Antibody Binding to Antigen

  • Outcomes of Antibody Binding to Antigen
    09:16

Introduction to Regulation of Gene Expression

  • Positive vs Negative Gene Regulation
    02:17
  • Introduction to Regulation of Gene Expression
    06:40

Introduction to Avoiding Host Defense Mechanisms

  • Introduction to Avoiding Host Defense Mechanisms
    01:59

1) Hide Within Host Cells

  • Hide Within Host Cells
    01:50

2) Avoiding Phagocytosis

  • Pathogen Use Capsules & M Proteins to Avoid Opsonization
    05:25
  • Pathogens Avoid Encounter with Phagocytes
    05:13
  • Pathogens Use Fc Receptors to Prevent Opsonization
    03:48

3) Surviving Inside Phagocytic Cells

  • Surviving Inside Phagocytic Cells
    04:18

4) Avoiding Complement System

  • Avoiding Complement System
    04:53

5) Avoiding Antibodies

  • Bacteria Avoid Antibodies by Producing IgA Proteases
    02:59
  • Bacteria Avoid Immune System by Mimicking Host Molecules
    03:11
  • Intro to Avoiding Antibodies
    01:35

Viruses Evade the Immune Response

  • 3) Viruses Avoid the Effects of Antibodies
    3:57
  • Intro to How Viruses Evade the Immune Response
    02:13
  • 2) Viruses Interfere with Antigen Presentation in Infected Cells
    3:43

Characteristics of Infectious Disease

  • Primary vs. Secondary Infections
    04:16
  • Communicable vs. Noncommunicable Diseases
    04:57
  • Intro to Characteristics of Infectious Disease
    05:09

Stages of Infectious Disease Progression

  • Stages of Infectious Disease Progression
    05:36
  • Chronic & Latent Infection Disease Progression
    05:14

Bacterial Pathogenesis

  • Intro to Bacterial Pathogenesis
    02:35
  • 1) Exposure to Pathogen
    03:27
  • 3) Invasion into Host Tissues
    05:38

Introduction to Pathogenic Toxins

  • Introduction to Pathogenic Toxins
    03:40

Exotoxins Cause Damage to the Host

  • 1) A-B Toxins
    04:44
  • Types of Exotoxins
    03:30
  • 3) Superantigens
    03:59

Endotoxin Causes Damage to the Host

  • Endotoxin
    02:46
  • Lipid A Causes Septic Shock
    03:24

Exotoxins vs. Endotoxin Review

  • Exotoxins vs. Endotoxin Review
    07:22

Introduction to Vaccines

  • History of Vaccines
    04:19
  • 2 Types of Vaccines
    02:03

Immunoassay: ELISA

  • Indirect ELISA
    02:50
  • Immunoassay: ELISA
    04:29
  • Direct ELISA (via "Sandwich" Method)
    03:56

Introduction to Microbial Genetics

  • Map of the Lesson on Microbial Genetics
    02:04
  • Introduction to Microbial Genetics
    04:20

Introduction to Mutations

  • Spontaneous vs. Induced Mutations
    02:47
  • Introduction to Mutations
    00:37
  • Types of Mutations
    08:44

Introduction to DNA Repair

  • Introduction to DNA Repair
    02:47

DNA Repair Mechanisms

  • Nucleotide Excision Repair
    03:31
  • SOS Repair System
    03:50
  • Photoreactivation
    02:29