Question 1

Which of the following DNA virus families is known for causing smallpox in humans, and what is a unique structural feature of this family?

Accepted Answer

Poxviridae; they have a complex, brick-shaped virion

Question 2

A patient presents with vesicular lesions around the mouth that recur periodically. Which DNA virus family is most likely responsible, and what is a key feature of its genome?

Accepted Answer

Herpesviridae; linear double-stranded DNA

Question 3

Which DNA virus family is associated with cervical cancer, and what is the primary mode of transmission?

Accepted Answer

Papillomaviridae; sexual contact

Question 4

Why are all viruses that cause chickenpox, shingles, and cold sores classified as Herpesviridae?

Accepted Answer

They all establish latent infections in host cells

Question 5

A laboratory technician is exposed to a DNA virus that is non-enveloped and causes respiratory infections. Which family does this virus most likely belong to?

Accepted Answer

Adenoviridae

Question 6

Which DNA virus family is unique for having a partially double-stranded, circular DNA genome and is associated with chronic liver disease?

Accepted Answer

Hepadnaviridae

Question 7

A child develops a 'slapped cheek' rash after exposure at school. Which DNA virus family is responsible, and what is a key feature of its genome?

Accepted Answer

Parvoviridae; single-stranded DNA

Question 8

Which of the following best describes the genome and envelope status of Polyomaviridae?

Accepted Answer

Circular double-stranded DNA; non-enveloped

Question 9

A vaccine is available for which of the following DNA virus families, and what disease does it primarily prevent?

Accepted Answer

Papillomaviridae; cervical cancer

Question 10

Which DNA virus family is most likely to be transmitted via contaminated needles and is associated with hepatocellular carcinoma?

Accepted Answer

Hepadnaviridae

Question 11

A patient with a compromised immune system develops progressive multifocal leukoencephalopathy. Which DNA virus family is implicated?

Accepted Answer

Polyomaviridae

Question 12

Which of the following equations best represents the relationship between the number of viral particles ($$N$$), the initial number ($$N_0$$), and the number of replication cycles ($$n) $$for a DNA virus that doubles each cycle?

Accepted Answer

$$N = N_0$ 	imes 2^n$$

Question 13

A DNA virus is found to replicate entirely in the cytoplasm of host cells, unlike most DNA viruses. Which family does it most likely belong to?

Accepted Answer

Poxviridae

Question 14

Which DNA virus family is most likely to cause conjunctivitis outbreaks in military barracks, and what is a key feature of its structure?

Accepted Answer

Adenoviridae; non-enveloped with icosahedral capsid

Question 15

A patient is diagnosed with hepatitis B. Which of the following statements about the causative virus is correct?

Accepted Answer

It has a partially double-stranded, circular DNA genome

Question 16

Which DNA virus family is most likely to cause warts on the hands and feet, and what is a key feature of its genome?

Accepted Answer

Papillomaviridae; circular double-stranded DNA

Question 17

A DNA virus is isolated from a patient with a severe skin infection. The virus is large, enveloped, and replicates in the cytoplasm. Which family does it most likely belong to?

Accepted Answer

Poxviridae

Question 18

Which of the following best explains why Herpesviridae viruses can cause recurrent infections?

Accepted Answer

They establish latency in host cells and can reactivate

Question 19

A DNA virus is found to have a single-stranded genome and is known to cause aplastic crisis in patients with sickle cell anemia. Which family does it belong to?

Accepted Answer

Parvoviridae

Question 20

Which of the following DNA virus families is most likely to be transmitted via the fecal-oral route and cause outbreaks of gastroenteritis in children?

Accepted Answer

Adenoviridae

Review of Pathogenic DNA Viruses

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