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Week 5a: Antimicrobial Drugs – Mechanisms, Spectrum, and Resistance

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Introduction to Antimicrobial Drugs

How Antimicrobial Drugs Work

Broad vs Narrow Spectrum Drugs

Superinfections

Inhibitors of Cell Wall Synthesis: Beta-lactam & Penicillin

Inhibitors of Protein Synthesis

Disruptors of Cell Membranes

Inhibitors of Nucleic Acid Synthesis

Competitive Inhibitors of Metabolic Pathways

Antifungal Drugs

Antiviral Drugs

Tests to Guide Antimicrobial Use

Antimicrobial Resistance