Estimate VLDL concentration from a fasting triglyceride value of 300 mg/dL using the commonly used approximation (VLDL = TG/5). Show calculations and state the implication for LDL risk if VLDL is that high.

• A. Estimated VLDL ≈ 300 mg/dL; VLDL equals triglyceride value and has no relationship to LDL.
• B. Estimated VLDL ≈ 60 mg/dL; this elevated level suggests greater future LDL production and increased atherosclerotic risk.
• C. Estimated VLDL ≈ 15 mg/dL using TG/20, indicating low risk and no concern for LDL changes.
• D. There is no valid method to approximate VLDL from triglycerides, so no inference about LDL can be made.

Answer: (B)