A toxicology study establishes a NOAEL for additive X at 50 mg/kg body weight/day. The regulatory safety factor applied is 100. A person weighs 70 kg and consumes 1.0 kg/day of a food containing additive X at 5 mg/kg food. Using stepwise calculations, determine (a) the acceptable daily intake (ADI) in mg/kg/day, (b) the maximum allowed mg/day for this person, and (c) the person's actual exposure in mg/kg/day and what percentage of the ADI this represents.

• A. ADI 50 mg/kg/day; allowed 3500 mg/day; exposure 0.0714 mg/kg/day (≈0.14% of ADI)
• B. ADI 0.5 mg/kg/day; allowed 35 mg/day; exposure 0.0714 mg/kg/day (≈14.3% of ADI)
• C. ADI 5 mg/kg/day; allowed 350 mg/day; exposure 0.714 mg/kg/day (≈14.3% of ADI)
• D. ADI 0.05 mg/kg/day; allowed 3.5 mg/day; exposure 0.0714 mg/kg/day (≈142.8% of ADI)

Answer: (B)