An unknown drug has a specific rotation of +82°. The commercial synthesis of this drug results in a mixture with an enantiomeric excess of 94 %.
i. Determine the absolute configuration of this drug.
ii. What is the percentage of each enantiomer in the commercial product?

• A. i. The absolute configuration of this drug is 'R'.ii. We can not determine the percentage of each enantiomer using the given data.
• B. i. The absolute configuration of this drug is 'S'.ii. (+) enantiomer = 94%, (-) enantiomer = 6%
• C. i. The absolute configuration of this drug is 'R'.ii. (+) enantiomer = 97%, (-) enantiomer = 3%
• D. i. We can not determine the absolute configuration of this drug with the given data.ii. (+) enantiomer = 97%, (-) enantiomer = 3%

Answer: (D)