Organic Chemistry
Draw the dipeptides formed in the reaction of N-protected alanine and glycine.
True or False. The bonds between the carbonyl carbon and nitrogen in the backbone of a peptide can freely rotate.
Specify the peptides generated by the cleavage of Ser-Gln-Arg-Val-Ile-Trp-Phe-Lys-Pro-Cys-Lys-Tyr-Met-Glu with trypsin.
Which tripeptide has a more readily cleaved C-terminal peptide bond by Carboxypeptidase A and why? Gly-Val-Glu or Gly-Val-Leu
Show how to prepare any of the standard amino acids from the compound shown below. You can use any reagents you need to accomplish the synthesis.
Consider the compound N-benzyloxycarbonyl isoleucine shown below:
Provide the equations for the formation (via acylation) and catalytic hydrogenolysis of N-benzyloxycarbonyl isoleucine.