Which tripeptide has a more readily cleaved C-terminal peptide bond by Carboxypeptidase A and why? Gly-Val-Glu or Gly-Val-Leu

• A. Gly-Val-Leu has a more readily cleaved C-terminal peptide bond by Carboxypeptidase A because Gly has a nonpolar substituent.
• B. Gly-Val-Glu has a more readily cleaved C-terminal peptide bond by Carboxypeptidase A because Gly has a polar substituent.
• C. Gly-Val-Leu has a more readily cleaved C-terminal peptide bond by Carboxypeptidase A because Leu has a nonpolar substituent.
• D. Gly-Val-Glu has a more readily cleaved C-terminal peptide bond by Carboxypeptidase A because Glu has a polar substituent.

Answer: (C)