Which of the following statements correctly describes hemoglobin carbonation?

• A. Hemoglobin carbonation occurs primarily in the lungs and involves the binding of O2 to hemoglobin.
• B. Hemoglobin carbonation occurs primarily in the tissues and involves the binding of O2 to hemoglobin.
• C. Hemoglobin carbonation occurs primarily in the tissues and involves the binding of CO2 to hemoglobin.
• D. Hemoglobin carbonation occurs primarily in the lungs and involves the binding of CO2 to hemoglobin.

Answer: (C)