17. Acid and Base Equilibrium / Ka and Kb / Problem 4
Problem 4
Alanine is an amino acid that can have both equilibria in water: H2N⎯CHCH3⎯COOH + H2O ⇌+H3N⎯CHCH3⎯COOH + OH-Kb = 7.4x10−5H2N⎯CHCH3⎯COOH + H2O ⇌H2N⎯CHCH3⎯COO- + H3O+ Ka = 4.5×10−3 It forms a zwitterion by intramolecular proton transfer H2N⎯CHCH3⎯COOH ⇌ +H3N⎯CHCH3⎯COO- Determine the equilibrium constant for the reaction using the given Ka and Kb values