Describe and give an example (real or hypothetical) of each of the following:

RNA interference

Write a short essay describing how an mRNA may be regulated in three different ways by specific cis-elements and RBPs.

Answer these questions concerning promoters.

What is the meaning of the term alternative promoter? How does the use of alternative promoters affect transcription?

Answer these questions concerning promoters.

Eukaryotic promoters are more variable than bacterial promoters. Explain why.

What features of eukaryotes provide additional opportunities for the regulation of gene expression compared to bacteria?

List three types of alternative splicing patterns and how they lead to the production of different protein isoforms.

Consider the CT/CGRP example of alternative splicing show. Which different types of alternative splicing patterns are represented?

Describe the roles of writers, readers, and erasers in eukaryotic gene regulation.