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Ch. 2 - Transmission Genetics
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172Non è quello che usi tu?Cambia libro di testo
Capitolo 2, Problema 48c

A pea plant that has the genotype RrGgwwdd is crossed to a plant that has the rrGgWwDd genotype. The R gene controls round versus wrinkled seed, the G gene controls yellow versus green seed, the W gene controls purple versus white flower, and the D gene controls tall versus short plants. Determine the following;


What proportion of the progeny are expected to have the genotype rrggwwdd?

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1
Step 1: Identify the genotypes of the parent plants. The first parent has the genotype RrGgwwdd, and the second parent has the genotype rrGgWwDd. Each gene pair represents a trait controlled by Mendelian inheritance.
Step 2: Determine the possible gametes produced by each parent. For the first parent (RrGgwwdd), the gametes are formed by combining one allele from each gene: R or r, G or g, w (only w since it's homozygous recessive), and d (only d since it's homozygous recessive). For the second parent (rrGgWwDd), the gametes are formed by combining r (only r since it's homozygous recessive), G or g, W or w, and D or d.
Step 3: Use a Punnett square or probability rules to calculate the likelihood of each progeny genotype. Focus on the specific genotype rrggwwdd. For each gene, calculate the probability of inheriting the required alleles: rr (from both parents), gg (from both parents), ww (from both parents), and dd (from both parents).
Step 4: Multiply the probabilities for each gene to find the overall probability of the progeny having the genotype rrggwwdd. Since the inheritance of each gene is independent, the probabilities can be multiplied together.
Step 5: Express the final proportion of progeny expected to have the genotype rrggwwdd as a fraction or percentage based on the calculated probability. Ensure all steps are clearly documented for understanding.

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Genotype and Phenotype

The genotype refers to the genetic makeup of an organism, represented by alleles (e.g., Rr, Gg). The phenotype is the observable physical or biochemical characteristics resulting from the genotype. Understanding the relationship between genotype and phenotype is crucial for predicting traits in offspring.
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Gamete Genotypes

Punnett Square

A Punnett square is a diagram used to predict the genetic outcomes of a cross between two organisms. It helps visualize the combination of alleles from each parent, allowing for the calculation of the expected proportions of different genotypes and phenotypes in the progeny.
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Chi Square Analysis

Independent Assortment

Independent assortment is a principle of genetics stating that alleles for different traits segregate independently during gamete formation. This means that the inheritance of one trait does not affect the inheritance of another, which is essential for calculating the probabilities of multiple traits in offspring.
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Gamete Genetics and Independent Assortment
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The accompanying pedigree shows a family in which one child (II-1) has an autosomal recessive condition. On the basis of this fact alone, provide the following information.

What is the chance that among the three children in generation II who have the dominant phenotype, one of them is AA and two of them are Aa? (Hint: Consider all possible orders of genotypes.)

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A pea plant that has the genotype RrGgwwdd is crossed to a plant that has the rrGgWwDd genotype. The R gene controls round versus wrinkled seed, the G gene controls yellow versus green seed, the W gene controls purple versus white flower, and the D gene controls tall versus short plants. Determine the following;


What are the phenotypes of each plant?

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Go to the OMIM website (http://www.ncbi.nlm.nih.gov/omim) and locate the Search button at the top of the page. Use the search function to look up, one by one, the following three human hereditary diseases that are relatively common in certain populations: 'Tay–Sachs disease' (select OMIM number 272800 from the search results list); 'cystic fibrosis' (select OMIM number 602421 from the search results list); and 'sickle cell anemia' (select OMIM 603903 from the search results list). For each of these diseases, look through the information and provide the following details:

On which chromosome is the gene for the disease located?

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Go to the OMIM website (http://www.ncbi.nlm.nih.gov/omim) and locate the Search button at the top of the page. Use the search function to look up, one by one, the following three human hereditary diseases that are relatively common in certain populations: 'Tay–Sachs disease' (select OMIM number 272800 from the search results list); 'cystic fibrosis' (select OMIM number 602421 from the search results list); and 'sickle cell anemia' (select OMIM 603903 from the search results list). For each of these diseases, look through the information and provide the following details:

What gene is mutated in the disease?

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A pea plant that has the genotype RrGgwwdd is crossed to a plant that has the rrGgWwDd genotype. The R gene controls round versus wrinkled seed, the G gene controls yellow versus green seed, the W gene controls purple versus white flower, and the D gene controls tall versus short plants. Determine the following;


What proportion of the progeny are expected to have the genotype RrGGwwDd?

432
views
Domanda del libro di testo

A pea plant that has the genotype RrGgwwdd is crossed to a plant that has the rrGgWwDd genotype. The R gene controls round versus wrinkled seed, the G gene controls yellow versus green seed, the W gene controls purple versus white flower, and the D gene controls tall versus short plants. Determine the following:

What proportion of the progeny are expected to be round, yellow, purple, and tall?

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