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Ch. 4 - Gene Interaction
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
4장, 문제 16

In cattle, an autosomal mutation called Dexter produces calves with short stature and short limbs. Embryos that are homozygous for the Dexter mutation have severely stunted development and either spontaneously abort or are stillborn. What progeny phenotypes do you expect from the cross of two Dexter cows? What are the expected proportions of the expected phenotypes?

검증된 단계별 안내
1
Step 1: Understand the genetic basis of the Dexter mutation. The mutation is autosomal and exhibits incomplete dominance. Heterozygous individuals (Dd) display the Dexter phenotype, while homozygous dominant individuals (DD) are non-viable and homozygous recessive individuals (dd) are normal.
Step 2: Set up a Punnett square for the cross between two Dexter cows, both of which are heterozygous (Dd). The possible gametes from each parent are D and d.
Step 3: Fill in the Punnett square by combining the gametes from each parent. The resulting genotypes will be: DD, Dd, Dd, and dd.
Step 4: Analyze the phenotypes associated with each genotype. DD embryos are non-viable and will not survive. Dd individuals will have the Dexter phenotype, and dd individuals will have the normal phenotype.
Step 5: Calculate the expected proportions of the phenotypes. From the Punnett square, the ratio of genotypes is 1 DD : 2 Dd : 1 dd. Since DD individuals are non-viable, the surviving progeny will consist of 2 Dexter (Dd) : 1 normal (dd), or 2/3 Dexter and 1/3 normal.

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주요 개념

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Autosomal Mutation

An autosomal mutation occurs in genes located on the autosomes, which are the non-sex chromosomes. In the case of the Dexter mutation in cattle, it affects growth and development, leading to phenotypes such as short stature. Understanding how these mutations are inherited is crucial for predicting the outcomes of genetic crosses.
추천 영상:
가이드 코스
09:08
Autosomal Pedigrees

Homozygosity and Phenotypic Expression

Homozygosity refers to having two identical alleles for a particular gene. In the context of the Dexter mutation, homozygous individuals exhibit severe developmental issues, leading to spontaneous abortion or stillbirth. This concept is essential for predicting the phenotypic ratios in offspring when crossing two Dexter cows, as it influences the viability of the progeny.
추천 영상:
가이드 코스
02:09
Penetrance and Expressivity

Punnett Square and Expected Ratios

A Punnett square is a tool used to predict the genotypic and phenotypic ratios of offspring from a genetic cross. By using the genotypes of the parent cows (e.g., homozygous Dexter vs. heterozygous), one can determine the expected proportions of phenotypes in the progeny. This method is fundamental for understanding inheritance patterns and calculating the likelihood of specific traits appearing in the offspring.
추천 영상:
가이드 코스
02:48
Chi Square Analysis
관련 실천
교과서 질문

The coat color in mink is controlled by two codominant alleles at a single locus. Red coat color is produced by the genotype R₁R₁, silver coat by the genotype R₁R₂, and platinum color by R₂R₂. White spotting of the coat is a recessive trait found with the genotype ss. Solid coat color is found with the S– genotype.


What are the expected progeny phenotypes and proportions for the cross SsR₁R₂ x ssR₂R₂?

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교과서 질문

The coat color in mink is controlled by two codominant alleles at a single locus. Red coat color is produced by the genotype R₁R₁, silver coat by the genotype R₁R₂, and platinum color by R₂R₂. White spotting of the coat is a recessive trait found with the genotype ss. Solid coat color is found with the S– genotype.


Two crosses are made between mink. Cross 1 is the cross of a solid, silver mink to one that is solid, platinum. Cross 2 is between a spotted, silver mink and one that is solid, silver. The progeny are described in the table below. Use these data to determine the genotypes of the parents in each cross. 

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교과서 질문

A plant line with reduced fertility comes to the attention of a plant breeder who observes that seed pods often contain a mixture of viable seeds that can be planted to produce new plants and withered seeds that cannot be sprouted. The breeder examines numerous seed pods in the reduced fertility line and counts 622 viable seeds and 204 nonviable seeds.

Propose an additional experiment to test the genetic mechanism you propose. If your hypothesis is correct, what experimental outcome do you predict?

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교과서 질문

Flower color in snapdragons results from the amount of the pigment anthocyanin in the petals. Red flowers are produced by plants that have full anthocyanin production, and ivory-colored flowers are produced by plants that lack the ability to produce anthocyanin. The allele An1 has full activity in anthocyanin production, and the allele An2 is a null allele. Dr. Ara B. Dopsis, a famous genetic researcher, crosses pure-breeding red snapdragons to pure-breeding ivory snapdragons and produces F₁ progeny plants that have pink flowers. He proposes that this outcome is the result of incomplete dominance, and he crosses the F₁ to test his hypothesis. What phenotypes does Dr. Dopsis predict will be found in the F₂, and in what proportions?

452
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교과서 질문

The coat color in mink is controlled by two codominant alleles at a single locus. Red coat color is produced by the genotype R₁R₁, silver coat by the genotype R₁R₂, and platinum color by R₂R₂. White spotting of the coat is a recessive trait found with the genotype ss. Solid coat color is found with the S– genotype.


If the cross SsR₁R₂ x SsR₁R₁ is made, what are the progeny phenotypes, and in what proportions are they expected to occur?

418
views
교과서 질문

A plant line with reduced fertility comes to the attention of a plant breeder who observes that seed pods often contain a mixture of viable seeds that can be planted to produce new plants and withered seeds that cannot be sprouted. The breeder examines numerous seed pods in the reduced fertility line and counts 622 viable seeds and 204 nonviable seeds.

What single-gene mechanism best explains the breeder's observation?

477
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