Skip to main content
Ch. 9 - The Molecular Biology of Translation
Sanders - Genetic Analysis: An Integrated Approach 3rd Edition
Sanders3rd EditionGenetic Analysis: An Integrated ApproachISBN: 9780135564172당신이 사용하는 게 아니라요?교과서 변경
9장, 문제 21b

In an experiment to decipher the genetic code, a poly-AC mRNA (ACACACAC...) is synthesized. What pattern of amino acids would appear if this sequence were to be translated by a mechanism that reads the genetic code as
A doublet with overlaps?

검증된 단계별 안내
1
Understand the problem: The poly-AC mRNA sequence (ACACACAC...) is being translated using a hypothetical mechanism that reads the genetic code as doublets with overlaps. This means that the ribosome reads two nucleotides at a time, and each doublet overlaps with the previous one by one nucleotide.
Identify the sequence of doublets: Since the mRNA sequence is ACACACAC..., the overlapping doublets would be: AC, CA, AC, CA, and so on. This pattern repeats throughout the sequence.
Determine the amino acids encoded by each doublet: Use a genetic code table that maps doublets to amino acids (note: this is hypothetical, as the real genetic code uses triplets). For example, if AC codes for one amino acid and CA codes for another, identify these amino acids.
Analyze the pattern of amino acids: Since the sequence alternates between AC and CA, the resulting amino acid sequence would alternate between the amino acids encoded by AC and CA. This creates a repeating pattern.
Summarize the findings: The translation of the poly-AC mRNA sequence using a doublet mechanism with overlaps would produce a repeating pattern of two amino acids, corresponding to the doublets AC and CA.

비슷한 문제에 대한 검증된 영상 답변:

이 영상 해법은 위 문제에 도움이 된다고 튜터들이 추천한 것입니다.
영상 길이:
2m
도움이 되었나요?

주요 개념

질문에 올바르게 답하기 위해 반드시 이해해야 하는 핵심 개념들은 다음과 같습니다.

Genetic Code

The genetic code is a set of rules that defines how sequences of nucleotides in DNA and RNA are translated into amino acids, the building blocks of proteins. It consists of codons, which are triplets of nucleotides, each corresponding to a specific amino acid. Understanding the genetic code is essential for predicting the amino acid sequence from a given mRNA.
추천 영상:
가이드 코스
11:43
The Genetic Code

Translation Mechanism

Translation is the process by which ribosomes synthesize proteins using mRNA as a template. In this context, the mechanism that reads the genetic code as a doublet with overlaps means that the ribosome reads two nucleotides at a time, potentially overlapping the reading frames. This approach can lead to different amino acid sequences than the standard triplet reading.
추천 영상:
가이드 코스
07:58
Translation initiation

Overlapping Codons

Overlapping codons occur when the reading frame of the genetic code allows for the same nucleotide sequence to be interpreted in multiple ways. In the case of doublet reading, each pair of nucleotides can form a codon that overlaps with the next, creating a unique pattern of amino acids. This concept is crucial for understanding how variations in reading frames can affect protein synthesis.
추천 영상:
가이드 코스
11:43
The Genetic Code