Question 1

Which of the following best describes the specificity of a B cell receptor (BCR)?

Accepted Answer

Each B cell generates a single BCR that recognizes only one epitope.

Question 2

Which antibody class is most prevalent in the blood and has the longest half-life?

Accepted Answer

IgG

Question 3

What is the primary function of plasma cells in adaptive immunity?

Accepted Answer

Secretion of antibodies

Question 4

Which of the following antibody classes is primarily associated with bodily secretions such as saliva and tears?

Accepted Answer

IgA

Question 5

A patient is experiencing an allergic reaction. Which antibody class is most likely involved?

Accepted Answer

IgE

Question 6

Which process ensures that B cells do not react against self-antigens during development?

Accepted Answer

Clonal deletion

Question 7

Which of the following is NOT a function of antibodies?

Accepted Answer

Direct killing of viruses inside host cells

Question 8

Which cytokine is responsible for stimulating B cells to differentiate into plasma cells?

Accepted Answer

Interleukin 4 (IL-4)

Question 9

What is the main action of tumor necrosis factor (TNF) in the immune response?

Accepted Answer

Triggers inflammation or apoptosis

Question 10

Which of the following best describes the structure of the antigen-binding site of an antibody?

Accepted Answer

Formed by the variable regions of both heavy and light chains

Question 11

A laboratory test detects the first antibody produced in response to a new infection. Which antibody class is being measured?

Accepted Answer

IgM

Question 12

Which of the following is a correct description of antibody-dependent cellular cytotoxicity (ADCC)?

Accepted Answer

Antibodies bind to target cells and recruit natural killer cells to induce apoptosis.

Question 13

Which cytokine is secreted by Th1 cells and increases phagocytosis by macrophages?

Accepted Answer

Gamma interferon (IFN-\gamma)

Question 14

Which of the following statements about IgD is correct?

Accepted Answer

Its exact function is not well understood.

Question 15

A patient with a parasitic worm infection is likely to have elevated levels of which antibody class?

Accepted Answer

IgE

Question 16

Which of the following best explains why a single B lymphocyte cannot recognize multiple antigenic determinants?

Accepted Answer

Each B cell expresses only one type of BCR, which is specific to a single epitope.

Question 17

Which of the following is a function of IgA antibodies?

Accepted Answer

Neutralization of pathogens in mucosal secretions

Question 18

Which cytokine is primarily responsible for the differentiation of helper T cells into Th1 cells?

Accepted Answer

Interleukin 12 (IL-12)

Question 19

Which antibody class is most effective at activating the classical complement pathway?

Accepted Answer

IgM

Question 20

A mutation prevents the formation of disulfide bonds in antibodies. Which of the following would most likely be affected?

Accepted Answer

The structural stability and proper folding of antibodies

Adaptive Immunity: B Lymphocytes and Antibodies

Study Guide - Practice Questions