Question 1

Which of the following best describes the principle of 'clonality' in adaptive immunity?

Accepted Answer

Once activated by a specific antigen, B or T cells multiply to produce many identical cells targeting that antigen.

Question 2

A patient receives an injection of pre-made antibodies after a snake bite. Which type of immunity is this?

Accepted Answer

Artificially acquired passive immunity

Question 3

Which antibody class is most effective at agglutination and is the first produced during an infection?

Accepted Answer

IgM

Question 4

What is the main function of MHC class I molecules?

Accepted Answer

Present endogenous antigens to Cytotoxic T cells (CD8+)

Question 5

Which lymphocyte is responsible for suppressing overactive immune responses and preventing autoimmunity?

Accepted Answer

Regulatory T cell (Tr)

Question 6

A newborn receives antibodies through breast milk. What type of immunity is this?

Accepted Answer

Naturally acquired passive immunity

Question 7

Which of the following is a function of antibodies in the immune response?

Accepted Answer

Neutralizing toxins and pathogens by binding to them

Question 8

Which cell type is the most important antigen-presenting cell (APC) for activating naive T cells?

Accepted Answer

Dendritic cell

Question 9

A patient receives a kidney transplant. Which molecules are most important for determining tissue compatibility?

Accepted Answer

MHC molecules

Question 10

Which of the following best describes the process of clonal deletion in the thymus?

Accepted Answer

T cells that do not recognize MHC or strongly recognize self-antigens undergo apoptosis.

Question 11

Which antibody class is most abundant in blood and can cross the placenta to protect the fetus?

Accepted Answer

IgG

Question 12

Which of the following is a unique feature of Helper T cell type 2 (Th2) compared to Th1?

Accepted Answer

Secretes Interleukin 4 and 5

Question 13

Which of the following best describes the role of opsonization in the immune response?

Accepted Answer

Antibodies bind to pathogens and mark them for phagocytosis.

Question 14

Which cell-surface glycoprotein is characteristic of Cytotoxic T cells (Tc)?

Accepted Answer

CD8

Question 15

A patient with a parasitic worm infection is likely to have elevated levels of which antibody class?

Accepted Answer

IgE

Question 16

Which of the following best explains why memory cells are important in adaptive immunity?

Accepted Answer

They allow for a faster and stronger response upon re-exposure to the same antigen.

Question 17

Which of the following is a function of Regulatory T cells (Tr)?

Accepted Answer

Suppress immune responses and prevent autoimmunity

Question 18

Which of the following is true about MHC II molecules?

Accepted Answer

They are found only on professional antigen-presenting cells.

Question 19

Which scenario best illustrates artificially acquired active immunity?

Accepted Answer

A child receives a vaccine and develops long-term immunity.

Question 20

Which of the following is a correct pairing of lymphocyte type and its notable secretion?

Accepted Answer

Cytotoxic T cell (Tc) – Perforin

Chapter 16: Adaptive Immunity – Study Notes

Study Guide - Practice Questions