Question 1

Which of the following best describes the genome structure of Bunyaviruses?

Accepted Answer

Segmented, negative-sense single-stranded RNA

Question 2

A patient presents with severe pneumonia after cleaning out a rodent-infested shed. Which virus is the most likely cause?

Accepted Answer

Hantavirus

Question 3

Which of the following is NOT a typical mode of transmission for Bunyaviruses?

Accepted Answer

Contaminated water

Question 4

Which laboratory technique is commonly used to diagnose infections caused by Bunyaviruses and Arenaviruses?

Accepted Answer

ELISA

Question 5

Why does Hepatitis D virus require Hepatitis B virus for virulence?

Accepted Answer

Hepatitis D virus cannot attach to liver cells without Hepatitis B surface antigen

Question 6

Which of the following viruses is transmitted primarily via the fecal-oral route?

Accepted Answer

Hepatitis A virus

Question 7

Arenaviruses are unique among RNA viruses because their virions contain:

Accepted Answer

Ribosomes

Question 8

Which of the following best explains why vaccination against Hepatitis B also prevents Hepatitis D infection?

Accepted Answer

Hepatitis D virus requires Hepatitis B virus to infect and replicate in liver cells

Question 9

Which of the following is a zoonotic disease caused by a Reoviridae family member and transmitted by ticks?

Accepted Answer

Colorado tick fever

Question 10

Rotavirus is a major cause of which clinical condition in infants, and what is the primary method of prevention?

Accepted Answer

Gastroenteritis; vaccination

Question 11

Which of the following statements about Hantaviruses is correct?

Accepted Answer

They are not considered arboviruses

Question 12

Arenaviruses can cause severe hemorrhagic fevers. Which of the following is a key prevention strategy?

Accepted Answer

Limiting contact with rodents

Question 13

Which of the following best describes the capsid symmetry and genome of Reoviridae?

Accepted Answer

Icosahedral capsid, double-stranded segmented RNA

Question 14

Which of the following viruses is associated with a high mortality rate in pregnant women?

Accepted Answer

Hepatitis E virus

Question 15

Which of the following is a common diagnostic method for Colorado tick fever?

Accepted Answer

Immunoassay

Question 16

Which of the following best explains why segmented genomes in viruses like Orthomyxoviridae and Bunyaviridae are clinically significant?

Accepted Answer

They enable genetic reassortment, leading to new viral strains

Question 17

A patient develops severe bleeding under the skin and into internal organs after traveling to West Africa. Which virus is most likely responsible?

Accepted Answer

Lassa virus

Question 18

Which of the following is a key difference between Rotavirus and Norovirus?

Accepted Answer

Rotavirus has a double-stranded segmented RNA genome, Norovirus has a single-stranded positive-sense RNA genome

Question 19

Which of the following best describes the prevention strategy for Rift Valley fever?

Accepted Answer

Vaccination and vector control

Question 20

Which of the following hepatitis viruses does NOT establish a chronic carrier state?

Accepted Answer

Hepatitis D virus

Pathogenic RNA Viruses: Structure, Diseases, and Taxonomy

Study Guide - Practice Questions