Which description best defines the acceptable daily intake (ADI) and explains why it is expressed in mg/kg body weight?

• A. ADI is the absolute minimum dose required to cause an adverse effect in humans and is expressed in mg/kg because it represents the international unit for caloric content of sweeteners.
• B. ADI is the estimated amount of a substance that can be consumed every day over a lifetime without appreciable health risk; it is expressed in mg/kg to scale the safe dose to body mass and individual metabolic capacity.
• C. ADI defines the exact recommended therapeutic dose to treat metabolic disorders with sweeteners and is measured in mg/kg to ensure standardized medical dosing.
• D. ADI is a government tax threshold for sweetener importation and is expressed in mg/kg to align with trade weight measures.

Answer: (B)