Create a short intervention plan that leverages dietary sources (not high-dose supplements) to support antioxidant defenses in older adults. Which combination best synthesizes biochemical principles and practical dietary guidance?

• A. Advise routine megadoses of isolated vitamin E and C for all older adults because dietary patterns are irrelevant and supplements are always more effective than whole foods at delivering antioxidants uniformly to every tissue.
• B. Promote a varied diet rich in fruits and vegetables (vitamin C and phytochemicals), nuts and seeds (vitamin E), adequate protein to maintain glutathione synthesis, and inclusion of healthy fats (to aid absorption of fat-soluble antioxidants), combined with reducing pro-oxidant exposures like smoking—this leverages complementary antioxidant systems rather than single high-dose supplements.
• C. Recommend exclusive reliance on a single antioxidant-rich food like blueberries and avoid all fats to ensure antioxidants remain water-soluble, because simplicity and single-food strategies are proven superior to diverse dietary patterns for antioxidant protection.
• D. Suggest complete avoidance of fruits and vegetables because their phytochemicals interfere with pharmacologic antioxidants and therefore make pharmaceutical interventions less effective; instead prioritize processed fortification products for predictable dosing.

Answer: (B)