the-two-most-general-amine-syntheses-are-the-reduction-of-amides-and-the-reducti

Question

The two most general amine syntheses are the reduction of amides and the reductive amination of carbonyl compounds. Show how to accomplish the synthesis shown below using one of the techniques described above.

Chemical reaction showing amide reduction to amine with an arrow indicating the process.

Accepted Answer

Amide reduction using thionyl chloride, ammonia, and lithium aluminum hydride.

Answer

Reaction steps for amide reduction using ammonia and lithium aluminum hydride.

Answer

Amide reduction process with methanol, hydrochloric acid, and lithium aluminum hydride.

Answer

Amide reduction with thionyl chloride, ammonia, sodium borohydride, and water.