Shown below are the structures of drugs and the diseases they treat. Predict whether the activity of these drugs will increase, decrease, or not be affected when taken with medicine for acid reflux diseases.

• A. (i) increase; (ii) decrease; (iii) decrease; (iv) increase
• B. (i) decrease; (ii) increase; (iii) increase; (iv) decrease
• C. (i) not affected; (ii) decrease; (iii) decrease; (iv) increase
• D. (i) increase; (ii) not affected; (iii) decrease; (iv) not affected

Answer: (A)