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Electrophilic Aromatic Substitution and Friedel-Crafts Reactions

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Electrophilic Aromatic Substitution – General Mechanism

  • EAS General Mechanism
    06:52
  • EAS Review
    03:07

Electrophilic Aromatic Substitution – Reactions

  • EAS Reactions Overview
    11:50

Generating Electrophiles – EAS Nitration

  • Reduction of Nitro Groups
    03:23
  • EAS Nitration
    06:09

Generating Electrophiles – EAS Halogenation

  • EAS Halogenation
    06:26

Generating Electrophiles – Friedel-Crafts Alkylation

  • Friedel-Crafts Alkylation
    06:30

Generating Electrophiles – Friedel-Crafts Acylation

  • Friedel-Crafts Acylation
    05:20

Carbocation Intermediates – Stability

  • Determining Carbocation Stability
    05:58
  • Predicting the most stable carbocation
    01:21

Directing Effects in Substituted Pyrroles, Furans, and Thiophenes

  • Guided course
    Directing Effects in Substituted Pyrroles, Furans, and Thiophenes Concept 2
    3:26
  • Guided course
    Directing Effects in Substituted Pyrroles, Furans, and Thiophenes Example 1
    1:20
  • Guided course
    Directing Effects in Substituted Pyrroles, Furans, and Thiophenes Concept 1
    2:02

EAS-o, p-Major Products

  • Ortho, Para major products
    04:42

EAS – Polysubstituted Benzene

  • EAS with Polysubstituted Benzene
    08:48

EAS – Sequence Groups

  • Sequence Groups
    04:42

EAS – Proposing Aromatic Synthesis

  • Synthesize the target molecule
    02:45
  • Aromatic synthesis starting with benzene/benzene derivatives
    02:49
  • Synthesize the target molecule
    05:21

SNAr Addition-Elimination Mechanism

  • The Meisenheimer Complex
    06:23
  • Which ipso-substitution is more favored
    03:30
  • General Mechanism
    06:45