Q: Which of the following is the correct order of increasing acidity?

$\mathrm{CH_4} < \mathrm{NH_3} < \mathrm{H_2O} < \mathrm{HF}$

Q: Which of the following is a meso compound?

2,3-dibromobutane (with S,R or R,S configuration)

Q: Which of the following statements about resonance is correct?

Resonance structures differ only in the arrangement of electrons, not atoms

Q: Which of the following statements about the E2 elimination reaction is correct?

The leaving group and the hydrogen must be anti-coplanar

Question 1

Which of the following molecules has the greatest bond angle according to VSEPR theory?

Accepted Answer

$\mathrm{CH_4}$ (methane)

Question 2

Which of the following is the most stable resonance structure for the acetate ion ($\mathrm{CH_3COO^-}$)?

Accepted Answer

Both oxygen atoms share the negative charge equally

Question 3

Which of the following conformations of butane has the lowest potential energy?

Accepted Answer

Anti conformation

Question 4

Which of the following compounds is the most acidic?

Accepted Answer

$\mathrm{CH_3COOH}$ (acetic acid)

Question 5

Which of the following is the correct IUPAC name for the compound $\mathrm{CH_3CH_2CH_2Br}$?

Accepted Answer

1-bromopropane

Question 6

Which of the following statements about SN1 and SN2 reactions is correct?

Accepted Answer

SN2 reactions proceed with inversion of configuration at the stereocenter

Question 7

Which of the following is the best nucleophile in a polar aprotic solvent?

Accepted Answer

$\mathrm{I^-}$

Question 8

Which of the following pairs are enantiomers?

Accepted Answer

A pair of molecules that are non-superimposable mirror images

Question 9

Which of the following statements about the addition of HBr to 2-butene is correct?

Accepted Answer

The major product is 2-bromobutane due to Markovnikov's rule

Question 10

Which of the following protons would appear furthest downfield (highest ppm) in a $^1$H NMR spectrum?

Accepted Answer

A proton on a carboxylic acid ($\mathrm{COOH}$)

Question 11

Which of the following is the correct order of increasing acidity?

Accepted Answer

$\mathrm{CH_4} < \mathrm{NH_3} < \mathrm{H_2O} < \mathrm{HF}$

Question 12

Which of the following best describes the hybridization of the central carbon in formaldehyde ($\mathrm{CH_2O}$)?

Accepted Answer

$sp^2$

Question 13

Which of the following is a meso compound?

Accepted Answer

2,3-dibromobutane (with S,R or R,S configuration)

Question 14

Which of the following statements about resonance is correct?

Accepted Answer

Resonance structures differ only in the arrangement of electrons, not atoms

Question 15

Which of the following is the best leaving group in a nucleophilic substitution reaction?

Accepted Answer

$\mathrm{I^-}$

Question 16

Which of the following statements about the E2 elimination reaction is correct?

Accepted Answer

The leaving group and the hydrogen must be anti-coplanar

Question 17

Which of the following is the product of the reaction of 2-methyl-2-butene with $\mathrm{H_2SO_4}$ and water?

Accepted Answer

2-methyl-2-butanol

Question 18

Which of the following best describes the splitting pattern for the methyl protons in ethyl acetate ($\mathrm{CH_3COOCH_2CH_3}$) in $^1$H NMR?

Accepted Answer

Triplet

Question 19

Which of the following is the major product when 2-bromopropane reacts with sodium ethoxide in ethanol?

Accepted Answer

Propene

Question 20

Which of the following statements about aromaticity is correct?

Accepted Answer

Aromatic compounds must be cyclic, planar, and follow Hückel's rule ($4n+2$ $\pi$ electrons)

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