Which of the following is TRUE regarding similarities between a gambling disorder and a substance use disorder?

• A. Both conditions typically produce medically diagnosable physiological withdrawal syndromes comparable in severity to opioid withdrawal.
• B. Both disorders show evidence of dysregulation in mesolimbic dopamine pathways and elicit similar cue-induced neural activation associated with craving.
• C. Pharmacotherapies approved and first-line for substance use disorders (e.g., methadone or buprenorphine) are widely effective and routinely recommended for a gambling disorder.
• D. Tolerance and impaired control are diagnostic features that occur only in substance use disorders and are not part of the diagnostic criteria for a gambling disorder.