Principles of Pathophysiology, 3rd edition

Comprehensive pathophysiology textbook for students studying nursing and allied health in Australia and New Zealand.

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Principles of Pathophysiology is a highly readable and accessible resource for busy students. Each chapter is co-authored by a scientist and an expert clinician, offering insight into how the science and clinical practice are linked.

Where possible, epidemiological data, lifespan issues, Indigenous issues, clinical practices, drug names, units of measurement and websites referenced are relevant to the Australian and New Zealand region.

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Key features

• What you should know before you start this chapter. These questions ensure that students review the basic bioscience principles and concepts that provide the foundation for the pathophysiological knowledge they will gain in the chapter.
• Clinical boxes. This feature highlights considerations specific to the successful clinical application of relevant knowledge to reduce the theory-practice gap.
• Indigenous health fast facts and cultural considerations. Important health concerns for Aboriginal and Torres Strait Islander peoples, Māori and Pacific Islands people are highlighted in relation to the issues presented in each chapter. Selected information is expanded on in the following separate section, Cultural considerations, to reflect more on the qualitative influence of indigeneity on health and wellness.
• Lifespan issues. Important health concerns or age-related principles specific to individuals across the age continuum - from neonates and children to older adults - are highlighted.
• Clinical snapshots. These concept maps are designed to demonstrate the critical links between pathophysiology, clinical manifestations and management. They are a key feature for integrating the science and clinical practice components of the text.
• Key clinical issues. This is a summary of the significant principles in each chapter that are central to providing safe, informed, clinical practice.
• Chapter review and Review questions. A summary of the key content essential to understanding the pathophysiological knowledge in each chapter is provided. Questions enable the student to assess, review and consolidate what they have learnt in the chapter.
• Health professional connections. Information on the inter-professional team management of specific disorders enables students to understand the roles and importance of the various health professionals they will work with.
• Case studies. Clinically accurate and realistic scenarios allow students to apply, synthesise and evaluate their knowledge, and in some instances predict clinical outcomes.

New to this edition

• COVID-19 updates. This edition reflects the major effect on human health the COVID-19 pandemic has had. Where appropriate, particular emphasis has been given to the pathophysiological effects of COVID-19 infection, both generally and more specifically on major body systems.
• Indigenous health fast facts and cultural considerations. The Indigenous health fast facts and cultural considerations sections at the end of most chapters have been updated to reflect the most recent epidemiological data available.
• New and revised images. A significant number of new and revised images have been produced for this edition. These images provide clearer understanding or representation of either new or reconceptualised content. Several new and revised clinical snapshots have also been constructed to accommodate the latest in best practice, to clarify previously included material, or to expand on content not previously addressed.