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Ch. 10 Molecular Biology of the Gene
Taylor - Campbell Biology: Concepts & Connections 10th Edition
Taylor, Simon, Dickey, Hogan10th EditionCampbell Biology: Concepts & ConnectionsISBN: 9780136538783Not the one you use?Change textbook
Chapter 10, Problem 11

Researchers working on the Human Genome Project have determined the nucleotide sequences of human genes and in many cases identified the proteins encoded by the genes. Knowledge of the nucleotide sequences of genes might be used to develop lifesaving medicines or treatments for genetic defects. In the United States, both government agencies and biotechnology companies have applied for patents on their discoveries of genes. In Britain, the courts have ruled that a naturally occurring gene cannot be patented. Do you think individuals and companies should be able to patent genes and gene products?

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1
Understand the concept of gene patenting: Gene patenting refers to the legal protection granted to individuals or companies for their discovery of a gene or its associated products, allowing them exclusive rights to use, modify, or sell the gene for a certain period.
Consider the ethical implications: Reflect on whether patenting genes aligns with ethical principles, such as whether it restricts access to lifesaving treatments or whether it incentivizes innovation in biotechnology.
Evaluate the scientific perspective: Analyze how patenting genes might impact research and collaboration in the scientific community. Does it encourage competition and innovation, or does it create barriers to sharing knowledge?
Examine the legal and societal context: Compare the legal stance in different countries, such as the United States allowing gene patents versus Britain ruling against them. Consider how these differences might affect global research and healthcare access.
Formulate a reasoned opinion: Based on the ethical, scientific, and legal considerations, develop a balanced perspective on whether individuals and companies should be able to patent genes and gene products, keeping in mind the potential benefits and drawbacks.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Human Genome Project

The Human Genome Project was an international scientific research initiative aimed at mapping and understanding all the genes of the human species. Completed in 2003, it provided a comprehensive sequence of human DNA, which has significant implications for medicine, genetics, and biotechnology. This project has enabled researchers to identify genetic variations associated with diseases, paving the way for personalized medicine and targeted therapies.
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Gene Patenting

Gene patenting refers to the legal practice of obtaining exclusive rights to specific sequences of DNA or the genes themselves. This practice raises ethical and legal questions, particularly regarding the ownership of naturally occurring genetic material. Proponents argue that patents incentivize innovation and investment in genetic research, while opponents contend that they hinder access to genetic information and treatments, especially for patients with genetic disorders.
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Ethical Implications of Genetic Research

The ethical implications of genetic research encompass concerns about privacy, consent, and the potential for discrimination based on genetic information. As advancements in genetics lead to new treatments and technologies, ethical considerations must address who has access to genetic data and how it is used. The debate over gene patenting exemplifies these ethical dilemmas, as it involves balancing innovation with the rights of individuals and the broader societal impact.
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Related Practice
Textbook Question

The nucleotide sequence of a DNA codon is GTA. A messenger RNA molecule with a complementary codon is transcribed from the DNA. In the process of protein synthesis, a transfer RNA pairs with the mRNA codon. What is the nucleotide sequence of the tRNA anticodon?

a. CAT

b. CUT

c. GUA

d. CAU

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Textbook Question
A cell containing a single chromosome is placed in a medium containing radioactive phosphate so that any new DNA strands formed by DNA replication will be radioactive. The cell replicates its DNA and divides. Then the daughter cells (still in the radioactive medium) replicate their DNA and divide, and a total of four cells are present. Sketch the DNA molecules in all four cells, showing a normal (nonradioactive) DNA strand as a solid line and a radioactive DNA strand as a dashed line.
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Textbook Question
The base sequence of the gene coding for a short polypeptide is CTACGCTAGGCGATTGACT. What would be the base sequence of the mRNA transcribed from this gene? Using the genetic code, give the amino acid sequence of the polypeptide translated from this mRNA. (Hint: What is the start codon?)
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Textbook Question
A mutation in a single gene may cause a major change in the body of a fruit fly, such as an extra pair of legs or wings. Yet it probably takes the combined action of hundreds or thousands of genes to produce a wing or leg. How can a change in just one gene cause such a big change in the body?
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Textbook Question
A chemical called dioxin is produced as a by-product of some chemical manufacturing processes. This substance was present in Agent Orange, a defoliant sprayed on vegetation during the Vietnam War. There has been a continuing controversy over its effects on soldiers exposed to it during the war. Animal tests have suggested that dioxin can be lethal and can cause birth defects, cancer, organ damage, and immune system suppression. But its effects on humans are unclear, and even animal tests are inconclusive. Researchers have discovered that dioxin enters a cell and binds to a protein that in turn attaches to the cell's DNA. How might this mechanism help explain the variety of dioxin's effects? How might you determine whether a particular individual became ill as a result of exposure to dioxin?
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