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Ch. 20 - The Molecular Revolution: Biotechnology, Genomics, and New Frontiers
Freeman - Biological Science 7th Edition
Freeman7th EditionBiological ScienceISBN: 9783584863285Not the one you use?Change textbook
Chapter 20, Problem 9

Revolutionaries executed Nicholas II, the last czar of Russia, along with his wife and five children, the family physician, and about a dozen servants. Many decades later, a grave said to hold the remains of the royal family was discovered. Biologists were asked to analyze DNA from the bodies. If the remains of the family were in this grave, predict how similar the DNA fingerprints would be between the parents, the children, and the unrelated individuals in the grave.

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Understand the concept of DNA fingerprinting: DNA fingerprinting is a method used to identify individuals based on their unique DNA profiles. This technique is often used in forensic science to match suspects with samples of DNA collected at a crime scene.
Recognize the genetic relationships: In a family, parents and their children share a significant amount of genetic material. Each child inherits half of their DNA from each parent, resulting in high similarity between the DNA of parents and their children.
Consider the unrelated individuals: The family physician and the servants, who are not genetically related to the royal family, would have distinctly different DNA profiles compared to the family members. Their DNA fingerprints would not show the same patterns of genetic markers that are seen in the family.
Predict the DNA fingerprint similarities: If the remains in the grave belong to the royal family and their servants, the DNA fingerprints of Nicholas II and his wife would show high similarity with their children's DNA. However, the DNA fingerprints of the unrelated individuals (the physician and servants) would show clear differences when compared to the family members.
Use of DNA fingerprinting in verification: By comparing the DNA fingerprints obtained from the remains to known profiles of the royal family, biologists can confirm whether the remains belong to the royal family and their associates. The degree of similarity between the DNA profiles would provide crucial evidence in verifying the identities of the individuals in the grave.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

DNA Fingerprinting

DNA fingerprinting is a technique used to identify individuals based on their unique DNA profiles. It involves analyzing specific regions of DNA that vary greatly among individuals, allowing for the comparison of genetic material. In the context of the royal family, DNA fingerprints can reveal genetic similarities and differences between family members and unrelated individuals.
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DNA Fingerprinting

Inheritance Patterns

Inheritance patterns describe how genetic traits are passed from parents to offspring. In sexually reproducing organisms, children inherit half of their DNA from each parent, leading to genetic similarities among siblings. This concept is crucial for predicting the DNA similarities between Nicholas II, his wife, and their children, as they would share a significant portion of their genetic material.
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Genetic Relatedness

Genetic relatedness refers to the degree of genetic similarity between individuals. Family members, such as parents and their children, share a higher genetic relatedness compared to unrelated individuals. In this case, the DNA analysis would show high similarity among the royal family members, while the unrelated individuals would exhibit distinct DNA profiles, highlighting the differences in genetic relatedness.
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Related Practice
Textbook Question

A friend who works in a research lab performed a GWAS and discovered a tight association between a SNP allele and the disease she is studying. She concluded that the SNP allele must be the mutation that causes the disease. Explain why she is likely to be wrong.

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Textbook Question
A friend who works in a research lab performed a GWAS and discovered a tight association between a SNP allele and the disease she is studying. She concluded that the SNP allele must be the mutation that causes the disease. Explain why she is likely to be wrong.
682
views
Textbook Question

Revolutionaries executed Nicholas II, the last czar of Russia, along with his wife and five children, the family physician, and about a dozen servants. Many decades later, a grave said to hold the remains of the royal family was discovered. Biologists were asked to analyze DNA from the bodies. If the remains of the family were in this grave, predict how similar the DNA fingerprints would be between the parents, the children, and the unrelated individuals in the grave.

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Textbook Question

One hypothesis for differences between humans and chimpanzees involves differences in gene regulation. A study using RNA-seq showed that the overall patterns of gene expression were similar in the liver and blood of the two species, but the expression patterns were strikingly different in the brain. How do these results relate to the hypothesis?

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Textbook Question

Potato blight causes potato plants to shrivel and rot. The disease is caused by the pathogen Phytophthora infestans, infamous for its role in Ireland's Great Potato Famine in the mid-1840s. The disease can devastate crops during wet weather, sometimes leading to total crop loss. Researchers aim to use recombinant DNA methods to transfer blight resistance genes from resistant varieties into susceptible varieties of potato. Explain how restriction endonucleases and DNA ligase could be used to insert a potato blight resistance gene into a plasmid.

682
views
Textbook Question
Potato blight causes potato plants to shrivel and rot. The disease is caused by the pathogen Phytophthora infestans, infamous for its role in Ireland's Great Potato Famine in the mid-1840s. The disease can devastate crops during wet weather, sometimes leading to total crop loss. Researchers aim to use recombinant DNA methods to transfer blight resistance genes from resistant varieties into susceptible varieties of potato.Explain how restriction endonucleases and DNA ligase could be used to insert a potato blight resistance gene into a plasmid.
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