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Riboswitches definitions
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Riboswitch
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Riboswitch
An mRNA sequence in the 5′ untranslated region that regulates gene expression by binding small molecules and altering RNA structure.
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Terms in this set (13)
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Riboswitch
An mRNA sequence in the 5′ untranslated region that regulates gene expression by binding small molecules and altering RNA structure.
5′ Untranslated Region
A segment of mRNA upstream of the coding sequence, not translated into protein, often involved in regulatory functions.
Aptamer Domain
An RNA segment within a riboswitch that specifically binds small ligands, initiating structural changes in the mRNA.
Expression Platform
A region of a riboswitch that forms secondary structures in response to ligand binding, modulating gene expression.
Terminator Structure
A secondary RNA structure that forms upon ligand binding, causing premature termination of transcription or translation.
Ligand
A small molecule that binds to the aptamer domain, triggering conformational changes in the riboswitch.
Secondary Structure
A folded RNA configuration, such as hairpins, formed within the expression platform to regulate gene activity.
Transcription Termination
A process where RNA synthesis is halted due to the formation of a terminator structure in the mRNA.
Translation Blockage
An event where ribosome access to the mRNA is prevented by structural changes, inhibiting protein synthesis.
Ribosome Binding Site
A sequence on mRNA where the ribosome attaches to initiate translation, which can be obstructed by riboswitches.
Prokaryotic Gene Regulation
Control of gene expression in organisms lacking a nucleus, often involving mechanisms like riboswitches.
RNA Nucleotide
A molecular building block of RNA, represented by letters such as A, U, G, and C, or by codes indicating possible variants.
Splicing
A process that can be influenced by riboswitches, involving the removal of non-coding sequences from RNA.